|
eF-site ID
|
6h3c-G |
PDB Code
|
6h3c |
Chain
|
G |
|
click to enlarge
|
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Title
|
Cryo-EM structure of the BRISC complex bound to SHMT2 |
Classification
|
SIGNALING PROTEIN |
Compound
|
BRISC complex subunit Abraxas 2 |
Source
|
(GLYM_HUMAN) |
|
Sequence
|
G: |
AVQAVHLESDAFLVCLNHALSTEKEEVMGLCIGELNDDTV
RIVHIHSVIILRRSDKRKDRVEISPEQLSAASTEAERLAE
LTGRPMRVVGWYHSHPHITVWPSHVDVRTQAMYQMMDQGF
VGLIFSCFIEDKNTKTGRVLYTCFQSIQAQYERIEIPIHI
VPHVTIGKVCLESAVELPKILCQEEQDAYRRIHSLTHLDS
VTKIHNGSVFTKNLCSQMSAVSGPLLQWLEDRLEQNQQHL
QELQQEKEELMQELSSLE
|
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Description
|
(1) |
BRCA1-A complex subunit Abraxas 1, Lys-63-specific deubiquitinase BRCC36 (E.C.3.4.19.-), BRISC and BRCA1-A complex member 2, BRISC and BRCA1-A complex member 1, BRCA1-A complex subunit RAP80
|
|
Functional site
|
|
1)
|
chain |
G |
residue |
122 |
type |
|
sequence |
H
|
description |
binding site for residue ZN G 401
|
source |
: AC2
|
|
2)
|
chain |
G |
residue |
124 |
type |
|
sequence |
H
|
description |
binding site for residue ZN G 401
|
source |
: AC2
|
|
3)
|
chain |
G |
residue |
135 |
type |
|
sequence |
D
|
description |
binding site for residue ZN G 401
|
source |
: AC2
|
|
|
|