eF-site ID 6h36-A PDB Code 6h36 Chain A click to enlarge Title The crystal structure of human carbonic anhydrase VII in complex with 4-(4-phenylpiperidine-1-carbonyl)benzenesulfonamide. Classification LYASE Compound Carbonic anhydrase 7 Source (CAH7_HUMAN) Sequence A:  GWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPS LQPLELSYEACMSLSITNNGHSVQVDFNDSDDRTVVTGGP LEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHLVHW NAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDA LYMVRFKGTKAQFSCFNPKSLLPASRHYWTYPGSLTTPPL SESVTWIVLREPISISERQMGKFRSLLFTSEDDERIHMVN NFRPPQPLKGRVVKASFRA Description Functional site 1) chain A residue 94 type sequence H description binding site for residue ZN A 301 source : AC1 2) chain A residue 96 type sequence H description binding site for residue ZN A 301 source : AC1 3) chain A residue 119 type sequence H description binding site for residue ZN A 301 source : AC1 4) chain A residue 92 type sequence Q description binding site for residue FKE A 302 source : AC2 5) chain A residue 94 type sequence H description binding site for residue FKE A 302 source : AC2 6) chain A residue 96 type sequence H description binding site for residue FKE A 302 source : AC2 7) chain A residue 119 type sequence H description binding site for residue FKE A 302 source : AC2 8) chain A residue 131 type sequence F description binding site for residue FKE A 302 source : AC2 9) chain A residue 143 type sequence V description binding site for residue FKE A 302 source : AC2 10) chain A residue 198 type sequence L description binding site for residue FKE A 302 source : AC2 11) chain A residue 199 type sequence T description binding site for residue FKE A 302 source : AC2 12) chain A residue 200 type sequence T description binding site for residue FKE A 302 source : AC2 13) chain A residue 105-121 type prosite sequence SEHTVDGKSFPSELHLV description ALPHA_CA_1 Alpha-carbonic anhydrases signature. SEHtVdgksFpsELHLV source prosite : PS00162 14) chain A residue 64 type ACT_SITE sequence H description Proton donor/acceptor => ECO:0000250|UniProtKB:P00918 source Swiss-Prot : SWS_FT_FI1 15) chain A residue 94 type BINDING sequence H description BINDING => ECO:0000269|Ref.13 source Swiss-Prot : SWS_FT_FI2 16) chain A residue 96 type BINDING sequence H description BINDING => ECO:0000269|Ref.13 source Swiss-Prot : SWS_FT_FI2 17) chain A residue 119 type BINDING sequence H description BINDING => ECO:0000269|Ref.13 source Swiss-Prot : SWS_FT_FI2 18) chain A residue 199 type BINDING sequence T description BINDING => ECO:0000250|UniProtKB:P00918 source Swiss-Prot : SWS_FT_FI3

Display surface Download Links