eF-site ID 6h23-J PDB Code 6h23 Chain J click to enlarge Title Crystal structure of the hClpP Y118A mutant with an activating small molecule Classification HYDROLASE Compound ATP-dependent Clp protease proteolytic subunit, mitochondrial Source (CLPP_HUMAN) Sequence J:  YDIYSRLLRERIVCVMGPIDDSVASLVIAQLLFLQSESNK KPIHMAINSPGGVVTAGLAIYDTMQYILNPICTWCVGQAA SMGSLLLAAGTPGMRHSLPNSRIMIHQPIAIQAEEIMKLK KQLYNIYAKHTKQSLQVIESAMERDRYMSPMEAQEFGILD KVLVHP Description (1)  ATP-dependent Clp protease proteolytic subunit, mitochondrial (E.C.3.4.21.92) Functional site 1) chain J residue 78 type sequence R description binding site for residue FJT J 301 source : AD4 2) chain J residue 79 type sequence L description binding site for residue FJT J 301 source : AD4 3) chain J residue 82 type sequence E description binding site for residue FJT J 301 source : AD4 4) chain J residue 146 type sequence W description binding site for residue FJT J 301 source : AD4 5) chain J residue 148 type sequence V description binding site for residue FJT J 301 source : AD4 6) chain J residue 101 type sequence A description binding site for residue FJT K 301 source : AD5 7) chain J residue 104 type sequence L description binding site for residue FJT K 301 source : AD5 8) chain J residue 105 type sequence F description binding site for residue FJT K 301 source : AD5 9) chain J residue 108 type sequence S description binding site for residue FJT K 301 source : AD5 10) chain J residue 138 type sequence Y description binding site for residue FJT K 301 source : AD5 11) chain J residue 153 type ACT_SITE sequence S description Nucleophile => ECO:0000269|PubMed:11923310 source Swiss-Prot : SWS_FT_FI1 12) chain J residue 178 type ACT_SITE sequence H description ACT_SITE => ECO:0000250 source Swiss-Prot : SWS_FT_FI2 13) chain J residue 200 type MOD_RES sequence K description N6-succinyllysine => ECO:0000250|UniProtKB:O88696 source Swiss-Prot : SWS_FT_FI3 14) chain J residue 211 type MOD_RES sequence K description N6-acetyllysine => ECO:0007744|PubMed:19608861 source Swiss-Prot : SWS_FT_FI4

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