eF-site ID 6h23-I PDB Code 6h23 Chain I click to enlarge Title Crystal structure of the hClpP Y118A mutant with an activating small molecule Classification HYDROLASE Compound ATP-dependent Clp protease proteolytic subunit, mitochondrial Source (CLPP_HUMAN) Sequence I:  YDIYSRLLRERIVCVMGPIDDSVASLVIAQLLFLQSESNK KPIHMAINSPGGVVTAGLAIYDTMQYILNPICTWCVGQAA SMGSLLLAAGTPGMRHSLPNSRIMIHQPDIAIQAEEIMKL KKQLYNIYAKHTKQSLQVIESAMERDRYMSPMEAQEFGIL DKVLVHP Description (1)  ATP-dependent Clp protease proteolytic subunit, mitochondrial (E.C.3.4.21.92) Functional site 1) chain I residue 79 type sequence L description binding site for residue FJT H 302 source : AD3 2) chain I residue 82 type sequence E description binding site for residue FJT H 302 source : AD3 3) chain I residue 84 type sequence I description binding site for residue FJT H 302 source : AD3 4) chain I residue 100 type sequence I description binding site for residue FJT J 301 source : AD4 5) chain I residue 101 type sequence A description binding site for residue FJT J 301 source : AD4 6) chain I residue 104 type sequence L description binding site for residue FJT J 301 source : AD4 7) chain I residue 105 type sequence F description binding site for residue FJT J 301 source : AD4 8) chain I residue 108 type sequence S description binding site for residue FJT J 301 source : AD4 9) chain I residue 138 type sequence Y description binding site for residue FJT J 301 source : AD4 10) chain I residue 153 type ACT_SITE sequence S description Nucleophile => ECO:0000269|PubMed:11923310 source Swiss-Prot : SWS_FT_FI1 11) chain I residue 178 type ACT_SITE sequence H description ACT_SITE => ECO:0000250 source Swiss-Prot : SWS_FT_FI2 12) chain I residue 200 type MOD_RES sequence K description N6-succinyllysine => ECO:0000250|UniProtKB:O88696 source Swiss-Prot : SWS_FT_FI3 13) chain I residue 211 type MOD_RES sequence K description N6-acetyllysine => ECO:0007744|PubMed:19608861 source Swiss-Prot : SWS_FT_FI4

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