eF-site ID 6h23-D PDB Code 6h23 Chain D click to enlarge Title Crystal structure of the hClpP Y118A mutant with an activating small molecule Classification HYDROLASE Compound ATP-dependent Clp protease proteolytic subunit, mitochondrial Source (CLPP_HUMAN) Sequence D:  YDIYSRLLRERIVCVMGPIDDSVASLVIAQLLFLQSESNK KPIHMAINSPGGVVTAGLAIYDTMQYILNPICTWCVGQAA SMGSLLLAAGTPGMRHSLPNSRIMIHQPIQAEEIMKLKKQ LYNIYAKHTKQSLQVIESAMERDRYMSPMEAQEFGILDKV LVHP Description Functional site 1) chain D residue 79 type sequence L description binding site for residue FJT D 301 source : AC4 2) chain D residue 82 type sequence E description binding site for residue FJT D 301 source : AC4 3) chain D residue 84 type sequence I description binding site for residue FJT D 301 source : AC4 4) chain D residue 146 type sequence W description binding site for residue FJT D 301 source : AC4 5) chain D residue 148 type sequence V description binding site for residue FJT D 301 source : AC4 6) chain D residue 100 type sequence I description binding site for residue FJT D 302 source : AC5 7) chain D residue 101 type sequence A description binding site for residue FJT D 302 source : AC5 8) chain D residue 104 type sequence L description binding site for residue FJT D 302 source : AC5 9) chain D residue 105 type sequence F description binding site for residue FJT D 302 source : AC5 10) chain D residue 108 type sequence S description binding site for residue FJT D 302 source : AC5 11) chain D residue 138 type sequence Y description binding site for residue FJT D 302 source : AC5 12) chain D residue 153 type ACT_SITE sequence S description Nucleophile => ECO:0000269|PubMed:11923310 source Swiss-Prot : SWS_FT_FI1 13) chain D residue 178 type ACT_SITE sequence H description ACT_SITE => ECO:0000250 source Swiss-Prot : SWS_FT_FI2 14) chain D residue 200 type MOD_RES sequence K description N6-succinyllysine => ECO:0000250|UniProtKB:O88696 source Swiss-Prot : SWS_FT_FI3 15) chain D residue 211 type MOD_RES sequence K description N6-acetyllysine => ECO:0007744|PubMed:19608861 source Swiss-Prot : SWS_FT_FI4

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