eF-site ID 6h23-C PDB Code 6h23 Chain C click to enlarge Title Crystal structure of the hClpP Y118A mutant with an activating small molecule Classification HYDROLASE Compound ATP-dependent Clp protease proteolytic subunit, mitochondrial Source (CLPP_HUMAN) Sequence C:  YDIYSRLLRERIVCVMGPIDDSVASLVIAQLLFLQSESNK KPIHMAINSPGGVVTAGLAIYDTMQYILNPICTWCVGQAA SMGSLLLAAGTPGMRHSLPNSRIMIHQPIAIQAEEIMKLK KQLYNIYAKHTKQSLQVIESAMERDRYMSPMEAQEFGILD KVLVHP Description (1)  ATP-dependent Clp protease proteolytic subunit, mitochondrial (E.C.3.4.21.92) Functional site 1) chain C residue 78 type sequence R description binding site for residue FJT B 301 source : AC3 2) chain C residue 79 type sequence L description binding site for residue FJT B 301 source : AC3 3) chain C residue 82 type sequence E description binding site for residue FJT B 301 source : AC3 4) chain C residue 84 type sequence I description binding site for residue FJT B 301 source : AC3 5) chain C residue 146 type sequence W description binding site for residue FJT B 301 source : AC3 6) chain C residue 148 type sequence V description binding site for residue FJT B 301 source : AC3 7) chain C residue 100 type sequence I description binding site for residue FJT D 301 source : AC4 8) chain C residue 101 type sequence A description binding site for residue FJT D 301 source : AC4 9) chain C residue 104 type sequence L description binding site for residue FJT D 301 source : AC4 10) chain C residue 105 type sequence F description binding site for residue FJT D 301 source : AC4 11) chain C residue 108 type sequence S description binding site for residue FJT D 301 source : AC4 12) chain C residue 138 type sequence Y description binding site for residue FJT D 301 source : AC4 13) chain C residue 153 type ACT_SITE sequence S description Nucleophile => ECO:0000269|PubMed:11923310 source Swiss-Prot : SWS_FT_FI1 14) chain C residue 178 type ACT_SITE sequence H description ACT_SITE => ECO:0000250 source Swiss-Prot : SWS_FT_FI2 15) chain C residue 200 type MOD_RES sequence K description N6-succinyllysine => ECO:0000250|UniProtKB:O88696 source Swiss-Prot : SWS_FT_FI3 16) chain C residue 211 type MOD_RES sequence K description N6-acetyllysine => ECO:0007744|PubMed:19608861 source Swiss-Prot : SWS_FT_FI4

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