eF-site ID 6h1y-AB
PDB Code 6h1y
Chain A, B

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Title CRYSTAL STRUCTURE OF A CHIMERIC VARIANT OF THIOREDOXIN FROM ESCHERICHIA COLI
Classification OXIDOREDUCTASE
Compound Thioredoxin 1,Thioredoxin (TrxA-1),Thioredoxin 1
Source (THIO_ECOLI)
Sequence A:  SDKIIHLTDDSFDEVIRNNKLILVDFWAEWCGPCKMIAPI
LDEIADEYQGKLTVAKLNIDQNPGTAPKYGIRGIPTLLLF
KNGEVAATKVGALSKGQLKEFLDANLA
B:  SDKIIHLTDDSFDEVIRNNKLILVDFWAEWCGPCKMIAPI
LDEIADEYQGKLTVAKLNIDQNPGTAPKYGIRGIPTLLLF
KNGEVAATKVGALSKGQLKEFLDANLA
Description


Functional site

1) chain A
residue 31
type ACT_SITE
sequence C
description Nucleophile
source Swiss-Prot : SWS_FT_FI1

2) chain A
residue 34
type ACT_SITE
sequence C
description Nucleophile
source Swiss-Prot : SWS_FT_FI1

3) chain B
residue 31
type ACT_SITE
sequence C
description Nucleophile
source Swiss-Prot : SWS_FT_FI1

4) chain B
residue 34
type ACT_SITE
sequence C
description Nucleophile
source Swiss-Prot : SWS_FT_FI1

5) chain A
residue 25
type SITE
sequence D
description Deprotonates C-terminal active site Cys
source Swiss-Prot : SWS_FT_FI2

6) chain B
residue 25
type SITE
sequence D
description Deprotonates C-terminal active site Cys
source Swiss-Prot : SWS_FT_FI2

7) chain A
residue 32
type SITE
sequence G
description Contributes to redox potential value
source Swiss-Prot : SWS_FT_FI3

8) chain A
residue 33
type SITE
sequence P
description Contributes to redox potential value
source Swiss-Prot : SWS_FT_FI3

9) chain B
residue 32
type SITE
sequence G
description Contributes to redox potential value
source Swiss-Prot : SWS_FT_FI3

10) chain B
residue 33
type SITE
sequence P
description Contributes to redox potential value
source Swiss-Prot : SWS_FT_FI3

11) chain A
residue 68
type MOD_RES
sequence K
description N6-acetyllysine => ECO:0000269|PubMed:18723842
source Swiss-Prot : SWS_FT_FI4

12) chain B
residue 68
type MOD_RES
sequence K
description N6-acetyllysine => ECO:0000269|PubMed:18723842
source Swiss-Prot : SWS_FT_FI4

13) chain A
residue 23-41
type prosite
sequence LVDFWAEWCGPCKMIAPIL
description THIOREDOXIN_1 Thioredoxin family active site. LVdFWaeWCGPCKmIapiL
source prosite : PS00194


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