eF-site ID 6h0f-H PDB Code 6h0f Chain H click to enlarge Title Structure of DDB1-CRBN-pomalidomide complex bound to IKZF1(ZF2) Classification SIGNALING PROTEIN Compound DNA damage-binding protein 1,DNA damage-binding protein 1,DNA damage-binding protein 1,DNA damage-binding protein 1 Source (IKZF1_HUMAN) Sequence H:  GRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVS MVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQ DFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPEC VLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQ KRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENL KDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRL RCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAA YVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTV AQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPD TEDEISPDKVILCL Description Functional site 1) chain H residue 323 type sequence C description binding site for residue ZN H 501 source : AC7 2) chain H residue 326 type sequence C description binding site for residue ZN H 501 source : AC7 3) chain H residue 391 type sequence C description binding site for residue ZN H 501 source : AC7 4) chain H residue 394 type sequence C description binding site for residue ZN H 501 source : AC7 5) chain H residue 351 type sequence N description binding site for residue Y70 H 502 source : AC8 6) chain H residue 352 type sequence P description binding site for residue Y70 H 502 source : AC8 7) chain H residue 353 type sequence H description binding site for residue Y70 H 502 source : AC8 8) chain H residue 377 type sequence E description binding site for residue Y70 H 502 source : AC8 9) chain H residue 378 type sequence H description binding site for residue Y70 H 502 source : AC8 10) chain H residue 379 type sequence S description binding site for residue Y70 H 502 source : AC8 11) chain H residue 380 type sequence W description binding site for residue Y70 H 502 source : AC8 12) chain H residue 386 type sequence W description binding site for residue Y70 H 502 source : AC8 13) chain H residue 400 type sequence W description binding site for residue Y70 H 502 source : AC8 14) chain H residue 402 type sequence F description binding site for residue Y70 H 502 source : AC8 15) chain H residue 323 type MOD_RES sequence C description N-acetylserine => ECO:0007744|PubMed:19413330 source Swiss-Prot : SWS_FT_FI1 16) chain H residue 326 type MOD_RES sequence C description N-acetylserine => ECO:0007744|PubMed:19413330 source Swiss-Prot : SWS_FT_FI1 17) chain H residue 378 type MOD_RES sequence H description N-acetylserine => ECO:0007744|PubMed:19413330 source Swiss-Prot : SWS_FT_FI1 18) chain H residue 380 type MOD_RES sequence W description N-acetylserine => ECO:0007744|PubMed:19413330 source Swiss-Prot : SWS_FT_FI1 19) chain H residue 386 type MOD_RES sequence W description N-acetylserine => ECO:0007744|PubMed:19413330 source Swiss-Prot : SWS_FT_FI1 20) chain H residue 391 type MOD_RES sequence C description N-acetylserine => ECO:0007744|PubMed:19413330 source Swiss-Prot : SWS_FT_FI1 21) chain H residue 394 type MOD_RES sequence C description N-acetylserine => ECO:0007744|PubMed:19413330 source Swiss-Prot : SWS_FT_FI1

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