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eF-site ID
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6h0f-G |
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PDB Code
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6h0f |
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Chain
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G |
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click to enlarge
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Title
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Structure of DDB1-CRBN-pomalidomide complex bound to IKZF1(ZF2) |
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Classification
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SIGNALING PROTEIN |
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Compound
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DNA damage-binding protein 1,DNA damage-binding protein 1,DNA damage-binding protein 1,DNA damage-binding protein 1 |
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Source
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(IKZF1_HUMAN) |
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Sequence
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G: |
MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLE
IYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFIL
TAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGI
IGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLE
ELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREK
EFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYH
NGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRL
FMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNG
VVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIV
DMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIKLHIRT
VPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALRP
SASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLII
DQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTA
MVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSMV
EFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALYL
KTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWM
SAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQE
VGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFGTVN
GMIGLVTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWR
SFHTERKTEPATGFIDGDLIESFLDISRPKMQEVVANLQY
DDGSGMKREATADDLIKVVEELTRIH
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Description
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Functional site
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1)
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chain |
G |
| residue |
2 |
| type |
MOD_RES |
| sequence |
S
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| description |
N-acetylserine => ECO:0007744|PubMed:19413330
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| source |
Swiss-Prot : SWS_FT_FI1
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