eF-site ID 6h0f-E PDB Code 6h0f Chain E click to enlarge Title Structure of DDB1-CRBN-pomalidomide complex bound to IKZF1(ZF2) Classification SIGNALING PROTEIN Compound DNA damage-binding protein 1,DNA damage-binding protein 1,DNA damage-binding protein 1,DNA damage-binding protein 1 Source (IKZF1_HUMAN) Sequence E:  GRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVS MVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQ DFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPEC VLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQ KRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENL KDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRL RCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAA YVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTV AQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPD TEDEISPDKVILCL Description Functional site 1) chain E residue 323 type sequence C description binding site for residue ZN E 501 source : AC4 2) chain E residue 326 type sequence C description binding site for residue ZN E 501 source : AC4 3) chain E residue 391 type sequence C description binding site for residue ZN E 501 source : AC4 4) chain E residue 394 type sequence C description binding site for residue ZN E 501 source : AC4 5) chain E residue 351 type sequence N description binding site for residue Y70 E 502 source : AC5 6) chain E residue 352 type sequence P description binding site for residue Y70 E 502 source : AC5 7) chain E residue 353 type sequence H description binding site for residue Y70 E 502 source : AC5 8) chain E residue 377 type sequence E description binding site for residue Y70 E 502 source : AC5 9) chain E residue 378 type sequence H description binding site for residue Y70 E 502 source : AC5 10) chain E residue 380 type sequence W description binding site for residue Y70 E 502 source : AC5 11) chain E residue 386 type sequence W description binding site for residue Y70 E 502 source : AC5 12) chain E residue 400 type sequence W description binding site for residue Y70 E 502 source : AC5 13) chain E residue 402 type sequence F description binding site for residue Y70 E 502 source : AC5 14) chain E residue 378 type MOD_RES sequence H description N-acetylserine => ECO:0007744|PubMed:19413330 source Swiss-Prot : SWS_FT_FI1 15) chain E residue 380 type MOD_RES sequence W description N-acetylserine => ECO:0007744|PubMed:19413330 source Swiss-Prot : SWS_FT_FI1 16) chain E residue 386 type MOD_RES sequence W description N-acetylserine => ECO:0007744|PubMed:19413330 source Swiss-Prot : SWS_FT_FI1 17) chain E residue 391 type MOD_RES sequence C description N-acetylserine => ECO:0007744|PubMed:19413330 source Swiss-Prot : SWS_FT_FI1 18) chain E residue 394 type MOD_RES sequence C description N-acetylserine => ECO:0007744|PubMed:19413330 source Swiss-Prot : SWS_FT_FI1 19) chain E residue 323 type MOD_RES sequence C description N-acetylserine => ECO:0007744|PubMed:19413330 source Swiss-Prot : SWS_FT_FI1 20) chain E residue 326 type MOD_RES sequence C description N-acetylserine => ECO:0007744|PubMed:19413330 source Swiss-Prot : SWS_FT_FI1

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