|
|
eF-site ID
|
6h0f-D |
|
PDB Code
|
6h0f |
|
Chain
|
D |
|
click to enlarge
|
|
|
Title
|
Structure of DDB1-CRBN-pomalidomide complex bound to IKZF1(ZF2) |
|
Classification
|
SIGNALING PROTEIN |
|
Compound
|
DNA damage-binding protein 1,DNA damage-binding protein 1,DNA damage-binding protein 1,DNA damage-binding protein 1 |
|
Source
|
(IKZF1_HUMAN) |
|
|
Sequence
|
D: |
MSYNYVVTAQKPTAVNGCVTGHFTSAEDLNLLIAKNTRLE
IYVVTAEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFIL
TAKYNACILEYKQSGESIDIITRAHGNVQDRIGRPSETGI
IGIIDPECRMIGLRLYDGLFKVIPLDRDNKELKAFNIRLE
ELHVIDVKFLYGCQAPTICFVYQDPQGRHVKTYEVSLREK
EFNKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYH
NGDKYLAIAPPIIKQSTIVCHNRVDPNGSRYLLGDMEGRL
FMLLLEKEEQMDGTVTLKDLRVELLGETSIAECLTYLDNG
VVFVGSRLGDSQLVKLNVDSNEQGSYVVAMETFTNLGPIV
DMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIQKLHIR
TVPLYESPRKICYQEVSQCFGVLSSRIEVQDTSGGTTALR
PSASTQALSSSVSSSKLFSSSTAPHETSFGEEVEVHNLLI
IDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGT
AMVYPEEAEPKQGRIVVFQYSDGKLQTVAEKEVKGAVYSM
VEFNGKLLASINSTVRLYEWTTEKELRTECNHYNNIMALY
LKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNW
MSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQ
EVGLFHLGEFVNVFCHGSLVMQTPTQGSVLFGTVNGMIGL
VTSLSESWYNLLLDMQNRLNKVIKSVGKIEHSFWRSFHTE
RKTEPATGFIDGDLIESFLDISRPKMQEVVANLQYDDGSG
MKREATADDLIKVVEELTRIH
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
D |
| residue |
2 |
| type |
MOD_RES |
| sequence |
S
|
| description |
N-acetylserine => ECO:0007744|PubMed:19413330
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
|