eF-site ID 6h0f-B PDB Code 6h0f Chain B click to enlarge Title Structure of DDB1-CRBN-pomalidomide complex bound to IKZF1(ZF2) Classification SIGNALING PROTEIN Compound DNA damage-binding protein 1,DNA damage-binding protein 1,DNA damage-binding protein 1,DNA damage-binding protein 1 Source (IKZF1_HUMAN) Sequence B:  GRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVS MVRNLIQKDRTFAVLAYSNVQEREAQFGTTAEIYAYREEQ DFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPEC VLPSTMSAVQLESLNKCQIFPSKPVSREDQCSYKWWQKYQ KRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLREWDENL KDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRL RCELDIMNKCTSLCCKQCQETEITTKNEIFSLSLCGPMAA YVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTV AQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPD TEDEISPDKVILCL Description Functional site 1) chain B residue 323 type sequence C description binding site for residue ZN B 501 source : AC1 2) chain B residue 326 type sequence C description binding site for residue ZN B 501 source : AC1 3) chain B residue 391 type sequence C description binding site for residue ZN B 501 source : AC1 4) chain B residue 394 type sequence C description binding site for residue ZN B 501 source : AC1 5) chain B residue 351 type sequence N description binding site for residue Y70 B 502 source : AC2 6) chain B residue 352 type sequence P description binding site for residue Y70 B 502 source : AC2 7) chain B residue 353 type sequence H description binding site for residue Y70 B 502 source : AC2 8) chain B residue 377 type sequence E description binding site for residue Y70 B 502 source : AC2 9) chain B residue 378 type sequence H description binding site for residue Y70 B 502 source : AC2 10) chain B residue 380 type sequence W description binding site for residue Y70 B 502 source : AC2 11) chain B residue 386 type sequence W description binding site for residue Y70 B 502 source : AC2 12) chain B residue 400 type sequence W description binding site for residue Y70 B 502 source : AC2 13) chain B residue 402 type sequence F description binding site for residue Y70 B 502 source : AC2 14) chain B residue 386 type MOD_RES sequence W description N-acetylserine => ECO:0007744|PubMed:19413330 source Swiss-Prot : SWS_FT_FI1 15) chain B residue 391 type MOD_RES sequence C description N-acetylserine => ECO:0007744|PubMed:19413330 source Swiss-Prot : SWS_FT_FI1 16) chain B residue 394 type MOD_RES sequence C description N-acetylserine => ECO:0007744|PubMed:19413330 source Swiss-Prot : SWS_FT_FI1

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