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eF-site ID
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6h04-J |
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PDB Code
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6h04 |
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Chain
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J |
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click to enlarge
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Title
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Closed conformation of the Membrane Attack Complex |
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Classification
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IMMUNE SYSTEM |
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Compound
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Complement component C9 |
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Source
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ORGANISM_COMMON: Human; ORGANISM_SCIENTIFIC: Homo sapiens; |
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Sequence
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J: |
SHIDCRMSPWSEWSQCDPCLRQMFRSRSIEVFGQFNGKRC
TDAVGDRRQCVPTEPCEDAEDDCGNDFQCSTGRCIKMRLR
CNGDNDCGDFSDEDDCESEPRPPCRDRVVEESELARTAGY
GINILGMDPLSTPFDNEFYNGLCNRDRDGNTLTYYRRPWN
VASLIYETKGEKNFRTEHYEEQIEAFKSIIQEKTSNFNAA
ISLKFTPSLHGKGSFRFSYSKNETYQLFLSYSSKKEKMFL
HVKGEIHLGRFVMRNRDVVLTTTFVDDIKALPTTYEKGEY
FAFLETYGTHYSSSGSLGGLYELIYVLDKASMKRKGVELK
DIKRCLGYHLDVSLAFSEISVGAEFNKDDCVKRGEGRAVN
ITSENLIDDVVSLIRGGTRKYAFELKEKLLRGTVIDVTDF
VNWASSINDAPVLISQKLSPIYNLVPVKMKNAHLKKQNLE
RAIEDYINEFSVRKCHTCQNGGTVILMDGKCLCACPFKFE
GIACEISKQKISEGLPALEFP
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Description
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(1) |
C9, Complement C5,Complement C5, Complement component C8 beta chain, Complement component C7, Complement component C8 gamma chain, Complement component C8 alpha chain, Complement component C6
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Functional site
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1)
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chain |
J |
| residue |
293-309 |
| type |
CARBOHYD |
| sequence |
VLTTTFVDDIKALPTTY
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| description |
C-linked (Man) tryptophan => ECO:0000269|PubMed:10551839
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| source |
Swiss-Prot : SWS_FT_FI1
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2)
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chain |
J |
| residue |
314-333 |
| type |
CARBOHYD |
| sequence |
YFAFLETYGTHYSSSGSLGG
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| description |
C-linked (Man) tryptophan => ECO:0000269|PubMed:10551839
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| source |
Swiss-Prot : SWS_FT_FI1
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3)
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chain |
J |
| residue |
244 |
| type |
CARBOHYD |
| sequence |
H
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| description |
C-linked (Man) tryptophan; partial => ECO:0000269|PubMed:10551839
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| source |
Swiss-Prot : SWS_FT_FI2
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4)
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chain |
J |
| residue |
27 |
| type |
CARBOHYD |
| sequence |
W
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| description |
O-linked (Fuc...) threonine => ECO:0000305|PubMed:22267737
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| source |
Swiss-Prot : SWS_FT_FI3
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5)
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chain |
J |
| residue |
30 |
| type |
CARBOHYD |
| sequence |
W
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| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:22267737
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| source |
Swiss-Prot : SWS_FT_FI4
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6)
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chain |
J |
| residue |
256 |
| type |
CARBOHYD |
| sequence |
N
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| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16335952
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| source |
Swiss-Prot : SWS_FT_FI5
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7)
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chain |
J |
| residue |
394 |
| type |
CARBOHYD |
| sequence |
N
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| description |
N-linked (GlcNAc...) (complex) asparagine => ECO:0000269|PubMed:14760718, ECO:0000269|PubMed:16263699, ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:19139490, ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:4055801
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| source |
Swiss-Prot : SWS_FT_FI6
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