eF-site ID 6gy2-B PDB Code 6gy2 Chain B click to enlarge Title Crystal structure of human Plk1-PBD in complex with WSSSLATPPTLSSpTVLI phosphopeptide from BRCA2 Classification CELL CYCLE Compound Serine/threonine-protein kinase PLK1 Source (6GY2) Sequence B:  DCHLSDMLQQLHSVNASKPSERGLVRQEEAEDPACIPIFW VSKWVDYSDKYGLGYQLCDNSVGVLFNDSTRLILYNDGDS LQYIERDGTESYLTVSSHPNSLMKKITLLKYFRNYMSEHL LKAGANITPREGDELARLPYLRTWFRTRSAIILHLSNGSV QINFFQDHTKLILCPLMAAVTYIDEKRDFRTYRLSLLEEY GCCKELASRLRYARTMVDKLLSSR Description Functional site 1) chain B residue 489 type sequence H description binding site for Ligand residues TPO C 207 through VAL C 208 bound to SER C 206 source : AC2 2) chain B residue 490 type sequence L description binding site for Ligand residues TPO C 207 through VAL C 208 bound to SER C 206 source : AC2 3) chain B residue 491 type sequence L description binding site for Ligand residues TPO C 207 through VAL C 208 bound to SER C 206 source : AC2 4) chain B residue 538 type sequence H description binding site for Ligand residues TPO C 207 through VAL C 208 bound to SER C 206 source : AC2 5) chain B residue 540 type sequence K description binding site for Ligand residues TPO C 207 through VAL C 208 bound to SER C 206 source : AC2 6) chain B residue 375 type MOD_RES sequence S description Phosphoserine => ECO:0007744|PubMed:18691976 source Swiss-Prot : SWS_FT_FI1 7) chain B residue 450 type MOD_RES sequence S description Phosphoserine => ECO:0007744|PubMed:18691976 source Swiss-Prot : SWS_FT_FI1 8) chain B residue 498 type MOD_RES sequence T description Phosphothreonine => ECO:0007744|PubMed:18691976 source Swiss-Prot : SWS_FT_FI2 9) chain B residue 492 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:23455478 source Swiss-Prot : SWS_FT_FI3

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