eF-site ID 6gsn-123 PDB Code 6gsn Chain 1, 2, 3 Title Structure of a partial yeast 48S preinitiation complex in closed conformation Classification RIBOSOME Compound 18S rRNA (1798-MER) Source ORGANISM_SCIENTIFIC: Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37); ORGANISM_COMMON: Yeast; Sequence 1:  AGCGCCGUGGCGCAGUGGAAGCGCGCAGGUCUCAUAAACC UGAUGUCCUCGGAUCGAAACCGAGCGGCGCUACCA 2:  UAUCUGGUUGAUCCUGCCAGUAGUCAUAUGCUUGUCUCAA AGAUUAAGCCAUGCAUGUCUAAGUAUAAGCAAUUUAUACA GUGAAACUGCGAAUGGCUCAUUAAAUCAGUUAUCGUUUAU UUGAUAGUUCCUUUACUACAUGGAUAUCUGUGGUAAUUCU AGAGCUAAUACAUGCUUAAAAUCUCGACCCUUUGGAAGAG AUGUAUUUAUUAGAUAAAAAAUCAAUGUCUUCGGACUCCU UGAUGAUUCAUAAUAACUUUUCGAAUCGCAUGGCCUUGUG CUGGCGAUGGUUCAUUCAAAUUUCUGCCCUAUCAACUUUC GAUGGUAGGAUAGUGGCCUACCAUGGUUUCAACGGGUAAC GGGGAAUAAGGGUUCGAUUCCGGAGAGGGAGCCUGAGAAA CGGCUACCACAUCCAAGGAAGGCAGCAGGCGCGCAAAUUA CCCAAUCCUAAUUCAGGGAGGUAGUGACAAUAAAUAACGA UACAGGGCCCAUUCGGGUCUUGUAAUUGGAAUGAGUACAA UGUAAAUACCUUAACGAGGAACAACUGGAGGGCAAGUCUG GUGCCAGCAGCCGCGGUAAUUCCAGCUCCAGUAGCGUAUA UUAAAGUUGUUGCAGUUAAAAAGCUCGUAGUUGAACUUUG GGUCUGGUUGUCCGGUCCGACUUUAUGUCGCGCACUGGUU UUCAACCGGAUCUUUCCUUCUGGCUAACCUGUACUCCUUG UGGGUGCAGGCGAACCAGGACUUUUACUUUGAAAAAAUUA GAGUGUUCAAAGCAGGCGAAAGCUCGAAUAUAUUAGCAUG GAAUAAUGGAAUAGGACGUUUGGUUCUAUUUUGUUGGUUU CUAGGACCAUCGUAAUGAUUAAUAGGGACGGUCGGGGGCA UCAGUAUUCAAUUGUCAGAGGUGAAAUUCUUGGAUUUAUU GAAGACUAACUACUGCGAAAGCAUUUGCCAAGGACGUUUU CAUUAAUCAAGAACGAAAGUUAGGGGAUCGAAGAUGAUCA GAUACCGUCGUAGUCUUAACCAUAAACUAUGCCGACUAGG GAUCGGGUGGUGUUUUUCUUAUGACCCACUCGGCACCUUA CGAGAAAUCAAAGUCUUUGGGUUCUGGGGGGAGUAUGGUC GCAAGGCUGAAACUUAAAGGAAUUGACGGAAGGGCACCAC CAGGAGUGGAGCCUGCGGCUUAAUUUGACUCAACACGGGG AAACUCACCAGGUCCAGACACAAUAAGGAUUGACAGAUUG AGAGCUCUUUCUUGAUUUUGUGGGUGGUGGUGCAUGGCCG UUCUUAGUUGGUGGAGUGAUUUGUCUGCUUAAUUGCGAUA ACGAACGAGACCUUAACCUACUAAAUAGGGUUGCUGGCAC UUGCCGGUUGACUCUUCUUAGAGGGACUAUCGGUUUCAAG CCGAUGGAAGUUUGAGGCAAUAACAGGUCUGUGAUGCCCU UAGACGUUCUGGGCCGCACGCGCGCUACACUGACGGAGCC AGCGAGUACAACCUUGGCCGAGAGGUCUGGGUAAUCUUGU GAAACUCCGUCGUGCUGGGGAUAGAGCAUUGUAAUUAUUG CUCUUCAACGAGGAAUUCCUAGUAAGCGCAAGUCAUCAGC UUGCGUUGAUUACGUCCCUGCCCUUUGUACACACCGCCCG UCGCUAGUACCGAUUGAAUGGCUUAGUGAGGCCUCAGGAU UUGCUUAGAGAAGGGGGCAACUCCAUCUCAGAGCGAAGAA UCUGGUCAAACUUGGUCAUUUAGAGGAACUAAAAGUCGUA ACAAGGUUUCCGUAGGUGAACCUGCGGAAGGAUCAUUA 3:  AUCUCUCUCUAUGC Description Functional site 1) chain 2 residue 361 type sequence G description binding site for residue MG 2 1801 source : AC1 2) chain 2 residue 362 type sequence G description binding site for residue MG 2 1801 source : AC1 3) chain 2 residue 93 type sequence A description binding site for residue MG 2 1802 source : AC2 4) chain 2 residue 95 type sequence G description binding site for residue MG 2 1802 source : AC2 5) chain 2 residue 402 type sequence G description binding site for residue MG 2 1802 source : AC2 6) chain 2 residue 553 type sequence C description binding site for residue MG 2 1803 source : AC3 7) chain 2 residue 554 type sequence A description binding site for residue MG 2 1803 source : AC3 8) chain 2 residue 555 type sequence A description binding site for residue MG 2 1803 source : AC3 9) chain 2 residue 44 type sequence U description binding site for residue MG 2 1804 source : AC4 10) chain 2 residue 100 type sequence A description binding site for residue MG 2 1804 source : AC4 11) chain 2 residue 1024 type sequence A description binding site for residue MG 2 1805 source : AC5 12) chain 2 residue 549 type sequence A description binding site for residue MG 2 1806 source : AC6 13) chain 2 residue 556 type sequence G description binding site for residue MG 2 1806 source : AC6 14) chain 2 residue 49 type sequence C description binding site for residue MG 2 1807 source : AC7 15) chain 2 residue 424 type sequence A description binding site for residue MG 2 1807 source : AC7 16) chain 2 residue 992 type sequence A description binding site for residue MG 2 1808 source : AC8 17) chain 2 residue 1776 type sequence G description binding site for residue MG 2 1808 source : AC8 18) chain 2 residue 1329 type sequence G description binding site for residue MG 2 1809 source : AC9 19) chain 2 residue 1331 type sequence C description binding site for residue MG 2 1809 source : AC9 20) chain 2 residue 1417 type sequence G description binding site for residue MG 2 1809 source : AC9 21) chain 2 residue 1418 type sequence C description binding site for residue MG 2 1809 source : AC9 22) chain 2 residue 573 type sequence G description binding site for residue MG 2 1810 source : AD1 23) chain 2 residue 1137 type sequence A description binding site for residue MG 2 1810 source : AD1 24) chain 2 residue 928 type sequence A description binding site for residue MG 2 1811 source : AD2 25) chain 2 residue 929 type sequence A description binding site for residue MG 2 1811 source : AD2 26) chain 2 residue 1761 type sequence A description binding site for residue MG 2 1812 source : AD3 27) chain 2 residue 1765 type sequence G description binding site for residue MG 2 1812 source : AD3 28) chain 2 residue 1766 type sequence G description binding site for residue MG 2 1812 source : AD3 29) chain 2 residue 1769 type sequence U description binding site for residue MG 2 1812 source : AD3 30) chain 2 residue 392 type sequence C description binding site for residue MG 2 1814 source : AD4 31) chain 2 residue 399 type sequence A description binding site for residue MG 2 1814 source : AD4 32) chain 2 residue 400 type sequence A description binding site for residue MG 2 1814 source : AD4 33) chain 2 residue 403 type sequence G description binding site for residue MG 2 1814 source : AD4 34) chain 2 residue 16 type sequence G description binding site for residue MG 2 1815 source : AD5 35) chain 2 residue 607 type sequence U description binding site for residue MG 2 1815 source : AD5 36) chain 2 residue 376 type sequence G description binding site for residue MG 2 1816 source : AD6 37) chain 2 residue 377 type sequence A description binding site for residue MG 2 1816 source : AD6 38) chain 2 residue 378 type sequence U description binding site for residue MG 2 1816 source : AD6 39) chain 2 residue 28 type sequence A description binding site for residue MG 2 1817 source : AD7 40) chain 2 residue 436 type sequence A description binding site for residue MG 2 1817 source : AD7 41) chain 2 residue 370 type sequence G description binding site for residue MG 2 1818 source : AD8 42) chain 2 residue 371 type sequence G description binding site for residue MG 2 1818 source : AD8 43) chain 2 residue 604 type sequence A description binding site for residue MG 2 1818 source : AD8 44) chain 2 residue 606 type sequence G description binding site for residue MG 2 1818 source : AD8 45) chain 2 residue 612 type sequence G description binding site for residue MG 2 1818 source : AD8 46) chain 2 residue 995 type sequence U description binding site for residue MG 2 1819 source : AD9 47) chain 2 residue 996 type sequence G description binding site for residue MG 2 1819 source : AD9 48) chain 2 residue 997 type sequence A description binding site for residue MG 2 1819 source : AD9 49) chain 2 residue 1003 type sequence U description binding site for residue MG 2 1819 source : AD9 50) chain 2 residue 42 type sequence G description binding site for residue MG 2 1820 source : AE1 51) chain 2 residue 44 type sequence U description binding site for residue MG 2 1821 source : AE2 52) chain 2 residue 46 type sequence A description binding site for residue MG 2 1821 source : AE2 53) chain 2 residue 47 type sequence A description binding site for residue MG 2 1821 source : AE2 54) chain 2 residue 1760 type sequence A description binding site for residue MG 2 1822 source : AE3 55) chain 2 residue 1761 type sequence A description binding site for residue MG 2 1822 source : AE3 56) chain 2 residue 1766 type sequence G description binding site for residue MG 2 1822 source : AE3 57) chain 2 residue 617 type sequence U description binding site for residue MG 2 1823 source : AE4 58) chain 2 residue 618 type sequence A description binding site for residue MG 2 1823 source : AE4 59) chain 2 residue 619 type sequence A description binding site for residue MG 2 1823 source : AE4 60) chain 2 residue 620 type sequence A description binding site for residue MG 2 1823 source : AE4 61) chain 2 residue 562 type sequence U description binding site for residue MG 2 1824 source : AE5 62) chain 2 residue 563 type sequence G description binding site for residue MG 2 1824 source : AE5 63) chain 2 residue 578 type sequence A description binding site for residue MG 2 1824 source : AE5 64) chain 2 residue 579 type sequence A description binding site for residue MG 2 1824 source : AE5 65) chain 2 residue 618 type sequence A description binding site for residue MG 2 1825 source : AE6 66) chain 2 residue 619 type sequence A description binding site for residue MG 2 1825 source : AE6 67) chain 2 residue 620 type sequence A description binding site for residue MG 2 1825 source : AE6 68) chain 2 residue 1328 type sequence A description binding site for residue MG 2 1826 source : AE7 69) chain 2 residue 1329 type sequence G description binding site for residue MG 2 1826 source : AE7 70) chain 2 residue 1330 type sequence A description binding site for residue MG 2 1826 source : AE7 71) chain 2 residue 621 type sequence A description binding site for residue MG 2 1827 source : AE8 72) chain 2 residue 622 type sequence A description binding site for residue MG 2 1827 source : AE8 73) chain 2 residue 100 type sequence A description binding site for residue MG 2 1828 source : AE9 74) chain 2 residue 101 type sequence U description binding site for residue MG 2 1828 source : AE9 75) chain 2 residue 358 type sequence A description binding site for residue MG 2 1828 source : AE9 76) chain 2 residue 360 type sequence C description binding site for residue MG 2 1828 source : AE9 77) chain 2 residue 604 type sequence A description binding site for residue MG 2 1829 source : AF1 78) chain 2 residue 1109 type sequence G description binding site for residue MG 2 1830 source : AF2 79) chain 2 residue 1110 type sequence G description binding site for residue MG 2 1830 source : AF2 80) chain 2 residue 95 type sequence G description binding site for residue MG 2 1831 source : AF3 81) chain 2 residue 1725 type sequence G description binding site for residue MG 2 1832 source : AF4 82) chain 2 residue 1726 type sequence U description binding site for residue MG 2 1832 source : AF4 83) chain 2 residue 1628 type sequence U description binding site for residue MG 2 1833 source : AF5 84) chain 2 residue 1790 type sequence G description binding site for residue MG 2 1833 source : AF5 85) chain 2 residue 1791 type sequence G description binding site for residue MG 2 1833 source : AF5 86) chain 2 residue 64 type sequence U description binding site for residue MG 2 1834 source : AF6 87) chain 2 residue 65 type sequence A description binding site for residue MG 2 1834 source : AF6 88) chain 2 residue 460 type sequence G description binding site for residue MG 2 1836 source : AF7 89) chain 2 residue 466 type sequence G description binding site for residue MG 2 1837 source : AF8 90) chain 2 residue 624 type sequence C description binding site for residue MG 2 1838 source : AF9 91) chain 2 residue 984 type sequence G description binding site for residue MG 2 1839 source : AG1 92) chain 2 residue 985 type sequence G description binding site for residue MG 2 1839 source : AG1 93) chain 2 residue 986 type sequence G description binding site for residue MG 2 1839 source : AG1 94) chain 2 residue 309 type sequence C description binding site for residue MG 2 1842 source : AG2 95) chain 2 residue 310 type sequence U description binding site for residue MG 2 1842 source : AG2 96) chain 2 residue 354 type sequence G description binding site for residue MG 2 1842 source : AG2 97) chain 2 residue 355 type sequence G description binding site for residue MG 2 1842 source : AG2 98) chain 2 residue 1005 type sequence C description binding site for residue MG 2 1843 source : AG3 99) chain 2 residue 421 type sequence G description binding site for residue MG 2 1844 source : AG4 100) chain 2 residue 422 type sequence G description binding site for residue MG 2 1844 source : AG4 101) chain 2 residue 1302 type sequence U description binding site for residue MG 2 1845 source : AG5 102) chain 2 residue 1303 type sequence G description binding site for residue MG 2 1845 source : AG5 103) chain 2 residue 1304 type sequence U description binding site for residue MG 2 1845 source : AG5 104) chain 2 residue 977 type sequence A description binding site for residue MG 2 1846 source : AG6 105) chain 2 residue 978 type sequence A description binding site for residue MG 2 1846 source : AG6 106) chain 2 residue 57 type sequence G description binding site for residue MG 2 1847 source : AG7 107) chain 2 residue 58 type sequence U description binding site for residue MG 2 1847 source : AG7 108) chain 2 residue 760 type sequence A description binding site for residue MG 2 1848 source : AG8 109) chain 2 residue 761 type sequence G description binding site for residue MG 2 1848 source : AG8 110) chain 2 residue 1139 type sequence G description binding site for residue MG 2 1849 source : AG9 111) chain 2 residue 1140 type sequence G description binding site for residue MG 2 1849 source : AG9 112) chain 2 residue 826 type sequence C description binding site for residue MG 2 1850 source : AH1 113) chain 2 residue 843 type sequence A description binding site for residue MG 2 1850 source : AH1 114) chain 2 residue 529 type sequence C description binding site for residue MG 2 1851 source : AH2 115) chain 2 residue 1293 type sequence G description binding site for residue MG 2 1852 source : AH3 116) chain 2 residue 1301 type sequence U description binding site for residue MG 2 1852 source : AH3 117) chain 2 residue 1302 type sequence U description binding site for residue MG 2 1852 source : AH3 118) chain 2 residue 937 type sequence G description binding site for residue MG 2 1853 source : AH4 119) chain 2 residue 939 type sequence A description binding site for residue MG 2 1853 source : AH4 120) chain 2 residue 988 type sequence U description binding site for residue MG 2 1854 source : AH5 121) chain 2 residue 1010 type sequence G description binding site for residue MG 2 1854 source : AH5 122) chain 2 residue 211 type sequence U description binding site for residue MG 2 1855 source : AH6 123) chain 2 residue 212 type sequence A description binding site for residue MG 2 1855 source : AH6 124) chain 2 residue 1537 type sequence G description binding site for residue MG 2 1856 source : AH7 125) chain 2 residue 1538 type sequence G description binding site for residue MG 2 1856 source : AH7 126) chain 2 residue 1539 type sequence G description binding site for residue MG 2 1856 source : AH7 127) chain 2 residue 334 type sequence U description binding site for residue MG 2 1857 source : AH8 128) chain 2 residue 335 type sequence G description binding site for residue MG 2 1857 source : AH8 129) chain 2 residue 874 type sequence G description binding site for residue MG 2 1858 source : AH9 130) chain 2 residue 875 type sequence G description binding site for residue MG 2 1858 source : AH9 131) chain 2 residue 378 type sequence U description binding site for residue MG 2 1859 source : AI1 132) chain 2 residue 379 type sequence U description binding site for residue MG 2 1859 source : AI1 133) chain 2 residue 1007 type sequence G description binding site for residue MG 2 1860 source : AI2 134) chain 2 residue 1054 type sequence U description binding site for residue MG 2 1861 source : AI3 135) chain 2 residue 923 type sequence A description binding site for residue MG 2 1862 source : AI4 136) chain 2 residue 1393 type sequence G description binding site for residue MG 2 1863 source : AI5 137) chain 2 residue 1281 type sequence U description binding site for residue MG 2 1864 source : AI6 138) chain 2 residue 1282 type sequence U description binding site for residue MG 2 1864 source : AI6 139) chain 2 residue 1284 type sequence U description binding site for residue MG 2 1864 source : AI6 140) chain 2 residue 1466 type sequence U description binding site for residue MG 2 1865 source : AI7 141) chain 2 residue 1467 type sequence A description binding site for residue MG 2 1865 source : AI7 142) chain 2 residue 1540 type sequence G description binding site for residue MG 2 1865 source : AI7 143) chain 2 residue 1444 type sequence A description binding site for residue MG 2 1866 source : AI8 144) chain 2 residue 1445 type sequence C description binding site for residue MG 2 1866 source : AI8 145) chain 2 residue 1199 type sequence G description binding site for residue MG 2 1867 source : AI9 146) chain 2 residue 1198 type sequence G description binding site for residue MG 2 1868 source : AJ1 147) chain 2 residue 1199 type sequence G description binding site for residue MG 2 1868 source : AJ1 148) chain 2 residue 1200 type sequence G description binding site for residue MG 2 1868 source : AJ1 149) chain 2 residue 1270 type sequence G description binding site for residue MG 2 1869 source : AJ2 150) chain 2 residue 1271 type sequence U description binding site for residue MG 2 1869 source : AJ2 151) chain 2 residue 1429 type sequence C description binding site for residue MG 2 1869 source : AJ2 152) chain 2 residue 1436 type sequence G description binding site for residue MG 2 1869 source : AJ2 153) chain 2 residue 1437 type sequence C description binding site for residue MG 2 1869 source : AJ2 154) chain 2 residue 1195 type sequence A description binding site for residue MG 2 1870 source : AJ3 155) chain 2 residue 1196 type sequence C description binding site for residue MG 2 1870 source : AJ3 156) chain 2 residue 1267 type sequence G description binding site for residue MG 2 1871 source : AJ4 157) chain 2 residue 1268 type sequence U description binding site for residue MG 2 1871 source : AJ4 158) chain 2 residue 1272 type sequence G description binding site for residue MG 2 1872 source : AJ5 159) chain 2 residue 1273 type sequence C description binding site for residue MG 2 1872 source : AJ5 160) chain 2 residue 1426 type sequence G description binding site for residue MG 2 1872 source : AJ5 161) chain 2 residue 1539 type sequence G description binding site for residue MG 2 1873 source : AJ6 162) chain 2 residue 1540 type sequence G description binding site for residue MG 2 1873 source : AJ6 163) chain 2 residue 1566 type sequence C description binding site for residue MG 2 1873 source : AJ6 164) chain 2 residue 1567 type sequence A description binding site for residue MG 2 1873 source : AJ6 165) chain 2 residue 1482 type sequence G description binding site for residue MG 2 1874 source : AJ7 166) chain 2 residue 1519 type sequence G description binding site for residue MG 2 1874 source : AJ7 167) chain 2 residue 1520 type sequence U description binding site for residue MG 2 1874 source : AJ7 168) chain 2 residue 1273 type sequence C description binding site for residue MG 2 1875 source : AJ8 169) chain 2 residue 1425 type sequence A description binding site for residue MG 2 1875 source : AJ8 170) chain 2 residue 1426 type sequence G description binding site for residue MG 2 1875 source : AJ8 171) chain 2 residue 1200 type sequence G description binding site for residue MG 2 1876 source : AJ9 172) chain 2 residue 1201 type sequence A description binding site for residue MG 2 1876 source : AJ9 173) chain 2 residue 1202 type sequence A description binding site for residue MG 2 1876 source : AJ9 174) chain 2 residue 1046 type sequence G description binding site for residue MG B 301 source : AK8 175) chain 2 residue 1764 type sequence A description binding site for residue MG a 102 source : AL1

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