eF-site ID 6gop-b
PDB Code 6gop
Chain b

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Title Yeast 20S Proteasome in complex with Homosalinosporamide A
Classification HYDROLASE
Compound Proteasome subunit alpha type-2
Source ORGANISM_COMMON: Baker's yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae (strain ATCC 204508 / S288c);
Sequence b:  TSIMAVTFKDGVILGADSRTTTGAYIANRVTDKLTRVHDK
IWCCRSGSAADTQAIADIVQYHLELYTSQYGTPSTETAAS
VFKELCYENKDNLTAGIIVAGYDDKNKGEVYTIPLGGSVH
KLPYAIAGSGSTFIYGYCDKNFRENMSKEETVDFIKHSLS
QAIKWDGSSGGVIRMVVLTAAGVERLIFYPDEYEQL
Description


Functional site

1) chain b
residue 45
type
sequence R
description binding site for residue CL b 202
source : AD5

2) chain b
residue 53
type
sequence Q
description binding site for residue CL b 202
source : AD5

3) chain b
residue 2
type
sequence S
description binding site for Di-peptide F6K b 201 and THR b 1
source : AD8

4) chain b
residue 17
type
sequence D
description binding site for Di-peptide F6K b 201 and THR b 1
source : AD8

5) chain b
residue 19
type
sequence R
description binding site for Di-peptide F6K b 201 and THR b 1
source : AD8

6) chain b
residue 20
type
sequence T
description binding site for Di-peptide F6K b 201 and THR b 1
source : AD8

7) chain b
residue 21
type
sequence T
description binding site for Di-peptide F6K b 201 and THR b 1
source : AD8

8) chain b
residue 23
type
sequence G
description binding site for Di-peptide F6K b 201 and THR b 1
source : AD8

9) chain b
residue 33
type
sequence K
description binding site for Di-peptide F6K b 201 and THR b 1
source : AD8

10) chain b
residue 45
type
sequence R
description binding site for Di-peptide F6K b 201 and THR b 1
source : AD8

11) chain b
residue 46
type
sequence S
description binding site for Di-peptide F6K b 201 and THR b 1
source : AD8

12) chain b
residue 47
type
sequence G
description binding site for Di-peptide F6K b 201 and THR b 1
source : AD8

13) chain b
residue 128
type
sequence G
description binding site for Di-peptide F6K b 201 and THR b 1
source : AD8

14) chain b
residue 129
type
sequence S
description binding site for Di-peptide F6K b 201 and THR b 1
source : AD8

15) chain b
residue 130
type
sequence G
description binding site for Di-peptide F6K b 201 and THR b 1
source : AD8

16) chain b
residue 166
type
sequence D
description binding site for Di-peptide F6K b 201 and THR b 1
source : AD8

17) chain b
residue 168
type
sequence S
description binding site for Di-peptide F6K b 201 and THR b 1
source : AD8

18) chain b
residue 169
type
sequence S
description binding site for Di-peptide F6K b 201 and THR b 1
source : AD8

19) chain b
residue 4-51
type prosite
sequence MAVTFKDGVILGADSRTTTGAYIANRVTDKLTRVHDKIWC
CRSGSAAD
description PROTEASOME_BETA_1 Proteasome beta-type subunits signature. ISMkYdnGVIIAADnlgsygsllrfngve.RlipvgdntvvgisGdiSD
source prosite : PS00854

20) chain b
residue 1
type ACT_SITE
sequence T
description Nucleophile => ECO:0000269|PubMed:9087403
source Swiss-Prot : SWS_FT_FI1


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