eF-site ID 6gml-A PDB Code 6gml Chain A click to enlarge Title Structure of paused transcription complex Pol II-DSIF-NELF Classification TRANSCRIPTION Compound DNA-directed RNA polymerase subunit Source ORGANISM_COMMON: Pig; ORGANISM_SCIENTIFIC: Sus scrofa; Sequence A:  SACPLRTIKRVQFGVLSPDELKRMSVTEGGIKYPETTEGG RPKLGGLMDPRQGVIERTGRCQTCAGNMTECPGHFGHIEL AKPVFHVGFLVKTMKVLRCVCFFCSKLLVDSNNPKIKDIL AKSKGQPKKRLTHVYDLCKGKNGGCGRYQPRIRRSGLELY AEWKKKILLSPERVHEIFKRISDEECFVLGMEPRYARPEW MIVTVLPVPPLSVRPAVRNQDDLTHKLADIVKINNQLRRN EQNGAAAHVIAEDVKLLQFHVATMVDNELPGLPRAMQKSG RPLKSLKQRLKGKEGRVRGNLMGKRVDFSARTVITPDPNL SIDQVGVPRSIAANMTFAEIVTPFNIDRLQELVRRGNSQY PGAKYIIRDNGDRIDLRFHPKPSDLHLQTGYKVERHMCDG DIVIFNRQPTLHKMSMMGHRVRILPWSTFRLNLSVTTPYN ADFDGDEMNLHLPQSLETRAEIQELAMVPRMIVTPQSNRP VMGIVQDTLTAVRKFTKRDVFLERGEVMNLLMFLSTWDGK VPQPAILKPRPLWTGKQIFSLIIPGHINCIRTHSTHPDDE DSGPYKHISPGDTKVVVENGELIMGILCKKSLGTSAGSLV HISYLEMGHDITRLFYSNIQTVINNWLLIEGHTIGIGDSI ADSKTYQDIQNTIKKAKQDVIEVIEKAHNNELEPTPGNTL RQTFENQVNRILNDARDKTGSSAQKSLSEYNNFKSMVVSG AKGSKINISQVIAVVGQQNVEGKRIPFGFKHRTLPHFIKD DYGPESRGFVENSYLAGLTPTEFFFHAMGGREGLIDTAVK TAETGYIQRRLIKSMESVMVKYDATVRNSINQVVQLRYGE DGLAGESVEFQNLATLKPSNKAFEKKFRFDYTNERALRRT LQEDLVKDVLSNAHIQNELEREFERMREDREVLRVIFPTG DSKVVLPCNLLRMIWNAQKIFHINPRLPSDLHPIKVVEGV KELSKKLVIVNGDDPLSRQAQENATLLFNIHLRSTLCSRR MAEEFRLSGEAFDWLLGEIESKFNQAIAHPGEMVGALAAQ SLGEPATQMTLNTFHYAGVSAKNVTLGVPRLKELINISKK PKTPSLTVFLLGQSARDAERAKDILCRLEHTTLRKVTANT AIYYDPNPQSTVVAEDQEWVNVISPWLLRVELDRKHMTDR KLTMEQIAEKINAGFGDDLNCIFNDDNAEKLVLRIRIMND DDVFLRCIESNMLTDMTLQGIEQISKVYMHLPQTDNKKKI IITEDGEFKALQEWILETDGVSLMRVLSEKDVDPVRTTSN DIVEIFTVLGIEAVRKALERELYHVISFDGSYVNYRHLAL LCDTMTCRGHLMAITRHGVNRQDTGPLMKCSFEETVDVLM EAAAHGESDPMKGVSENIMLGQLAPAGTGCFDLLLDAEKC KYGMEIP Description (1)  DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, RNA polymerase II subunit C, RNA polymerase II subunit E, RNA polymerase II subunit F, DNA-directed RNA polymerases I, II, and III subunit RPABC3, DNA-directed RNA polymerase II subunit RPB9, Uncharacterized protein, Negative elongation factor A, Negative elongation factor B, Negative elongation factor C/D, Negative elongation factor E, Transcription elongation factor SPT4, Transcription elongation factor SPT5, RNA polymerase II subunit D, RNA polymerase II subunit G/DNA Complex Functional site 1) chain A residue 495 type sequence D description binding site for residue MG A 2001 source : AC1 2) chain A residue 497 type sequence D description binding site for residue MG A 2001 source : AC1 3) chain A residue 499 type sequence D description binding site for residue MG A 2001 source : AC1 4) chain A residue 111 type sequence C description binding site for residue ZN A 2002 source : AC2 5) chain A residue 114 type sequence C description binding site for residue ZN A 2002 source : AC2 6) chain A residue 183 type sequence G description binding site for residue ZN A 2002 source : AC2 7) chain A residue 71 type sequence C description binding site for residue ZN A 2003 source : AC3 8) chain A residue 74 type sequence C description binding site for residue ZN A 2003 source : AC3 9) chain A residue 81 type sequence C description binding site for residue ZN A 2003 source : AC3 10) chain A residue 84 type sequence H description binding site for residue ZN A 2003 source : AC3

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