|
|
eF-site ID
|
6gml-I |
|
PDB Code
|
6gml |
|
Chain
|
I |
|
click to enlarge
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Title
|
Structure of paused transcription complex Pol II-DSIF-NELF |
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Classification
|
TRANSCRIPTION |
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Compound
|
DNA-directed RNA polymerase subunit |
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Source
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ORGANISM_COMMON: Pig; ORGANISM_SCIENTIFIC: Sus scrofa; |
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Sequence
|
I: |
PGFVGIRFCQECNNMLYPKEDKENRILLYACRNCDYQQEA
DNSCIYVNKITHEVDELTQIIADVSQDPTLPRTEDHPCQK
CGHKEAVFFQSHSARAEDAMRLYYVCTAPHCGHRWTE
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|
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Description
|
(1) |
DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, RNA polymerase II subunit C, RNA polymerase II subunit E, RNA polymerase II subunit F, DNA-directed RNA polymerases I, II, and III subunit RPABC3, DNA-directed RNA polymerase II subunit RPB9, Uncharacterized protein, Negative elongation factor A, Negative elongation factor B, Negative elongation factor C/D, Negative elongation factor E, Transcription elongation factor SPT4, Transcription elongation factor SPT5, RNA polymerase II subunit D, RNA polymerase II subunit G/DNA Complex
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Functional site
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|
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1)
|
chain |
I |
| residue |
17 |
| type |
|
| sequence |
C
|
| description |
binding site for residue ZN I 200
|
| source |
: AC6
|
|
|
2)
|
chain |
I |
| residue |
20 |
| type |
|
| sequence |
C
|
| description |
binding site for residue ZN I 200
|
| source |
: AC6
|
|
|
3)
|
chain |
I |
| residue |
39 |
| type |
|
| sequence |
C
|
| description |
binding site for residue ZN I 200
|
| source |
: AC6
|
|
|
4)
|
chain |
I |
| residue |
42 |
| type |
|
| sequence |
C
|
| description |
binding site for residue ZN I 200
|
| source |
: AC6
|
|
|
5)
|
chain |
I |
| residue |
86 |
| type |
|
| sequence |
C
|
| description |
binding site for residue ZN I 201
|
| source |
: AC7
|
|
|
6)
|
chain |
I |
| residue |
89 |
| type |
|
| sequence |
C
|
| description |
binding site for residue ZN I 201
|
| source |
: AC7
|
|
|
7)
|
chain |
I |
| residue |
114 |
| type |
|
| sequence |
C
|
| description |
binding site for residue ZN I 201
|
| source |
: AC7
|
|
|
8)
|
chain |
I |
| residue |
119 |
| type |
|
| sequence |
C
|
| description |
binding site for residue ZN I 201
|
| source |
: AC7
|
|
|
9)
|
chain |
I |
| residue |
121 |
| type |
|
| sequence |
H
|
| description |
binding site for residue ZN I 201
|
| source |
: AC7
|
|
|
10)
|
chain |
I |
| residue |
20 |
| type |
MOD_RES |
| sequence |
C
|
| description |
Phosphoserine => ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
11)
|
chain |
I |
| residue |
39 |
| type |
MOD_RES |
| sequence |
C
|
| description |
Phosphoserine => ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
12)
|
chain |
I |
| residue |
42 |
| type |
MOD_RES |
| sequence |
C
|
| description |
Phosphoserine => ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
13)
|
chain |
I |
| residue |
112-118 |
| type |
prosite |
| sequence |
YVCTAPH
|
| description |
IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YVCTAPH
|
| source |
prosite : PS00290
|
|
|
14)
|
chain |
I |
| residue |
86-123 |
| type |
prosite |
| sequence |
CQKCGHKEAVFFQSHSARAEDAMRLYYVCTAPHCGHRW
|
| description |
ZF_TFIIS_1 Zinc finger TFIIS-type signature. CqkCghkeavffqSHSARaEDAmrlyyvCtaph.CghrW
|
| source |
prosite : PS00466
|
|
|
15)
|
chain |
I |
| residue |
16-42 |
| type |
prosite |
| sequence |
FCQECNNMLYPKEDKENRILLYACRNC
|
| description |
RNA_POL_M_15KD RNA polymerases M / 15 Kd subunits signature. FCqECNNMLypkedkenrillyaCrnC
|
| source |
prosite : PS01030
|
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