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eF-site ID
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6gff-I |
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PDB Code
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6gff |
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Chain
|
I |
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click to enlarge
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Title
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Structure of GARP (LRRC32) in complex with latent TGF-beta1 and MHG-8 Fab |
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Classification
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IMMUNE SYSTEM |
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Compound
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Transforming growth factor beta-1 |
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Source
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ORGANISM_COMMON: Mouse; ORGANISM_SCIENTIFIC: Mus musculus; |
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Sequence
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I: |
HQDKVPCKMVDKKVSCQVLGLLQVPSVLPPDTETLDLSGN
QLRSILASPLGFYTALRHLDLSTNEISFLQPGAFQALTHL
EHLSLAHNRLAMATALSAGGLGPLPRVTSLDLSGNSLYSG
LLERLLGEAPSLHTLSLAENSLTRLTRHTFRDMPALEQLD
LHSNVLMDIEDGAFEGLPRLTHLNLSRNSLTCISDFSLQQ
LRVLDLSCNSIEAFQTASQPQAEFQLTWLDLRENKLLHFP
DLAALPRLIYLNLSNNLIRLPIHAPSEGWSARPLSQLLNL
DLSYNEIELIPDSFLEHLTSLCFLNLSRNCLRTFEARRLG
SLPCLMLLDLSHNALETLELGARALGSLRTLLLQGNALRD
LPPYTFANLASLQRLNLQGNRVSPCGGPDEPGPSGCVAFS
GITSLRSLSLVDNEIELLRAGAFLHTPLTELDLSSNPGLE
VATGALGGLEASLEVLALQGNGLMVLQVDLPCFICLKRLN
LAENRLSHLPAWTQAVSLEVLDLRNNSFSLLPGSAMGGLE
TSLRRLYLQGNPLSCCGNGWLAAQLHQGRVD
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Description
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(1) |
Transforming growth factor beta-1, Leucine-rich repeat-containing protein 32, MHG-8 Fab light chain, MHG-8 Fab heavy chain
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Functional site
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1)
|
chain |
I |
| residue |
203 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000255
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| source |
Swiss-Prot : SWS_FT_FI2
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2)
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chain |
I |
| residue |
271 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000255
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
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3)
|
chain |
I |
| residue |
345 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000255
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
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4)
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chain |
I |
| residue |
545 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000255
|
| source |
Swiss-Prot : SWS_FT_FI2
|
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