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eF-site ID
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6g9p-A |
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PDB Code
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6g9p |
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Chain
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A |
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click to enlarge
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Title
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Structural basis for the inhibition of E. coli PBP2 |
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Classification
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HYDROLASE/ANTIBIOTIC |
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Compound
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Peptidoglycan D,D-transpeptidase MrdA |
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Source
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(MRDA_ECOLI) |
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Sequence
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A: |
NRIKLVPIAPSRGIIYDRNGIPLALNRTIYQIEMMPEKVD
NVQQTLDALRSVVDLTDDDIAAFRKERARSHRFTSIPVKT
NLTEVQVARFAVNQYRFPGVEVKGYKRRYYPYGSALTHVI
GYVSKINDKDVERLNNDGKLANYAATHDIGKLGIERYYED
VLHGQTGYEEVEVNNRGRVIRQLKEVPPQAGHDIYLTLDL
KLQQYIETLLAGSRAAVVVTDPRTGGVLALVSTPSYDPNL
FVDGISSKDYSALLNDPNTPLVNRATQGVYPPASTVKPYV
AVSALSAGVITRNTTLFDPGWWQLPGSEKRYRDWKKWGHG
RLNVTRSLEESADTFFYQVAYDMGIDRLSEWMGKFGYGHY
TGIDLAEERSGNMPTREWKQKRFKKPWYQGDTIPVGIGQG
YWTATPIQMSKALMILINDGIVKVPHLLMSTAEDGKQVPW
VQPHEPPVGDIHSGYWELAKDGMYGVANRPNGTAHKYFAS
APYKIAAKSGTAQRDHKLMTAFAPYNNPQVAVAMILENGG
AGPAVGTLMRQILDHIML
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Description
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Functional site
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1)
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chain |
A |
| residue |
330 |
| type |
ACT_SITE |
| sequence |
S
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| description |
Acyl-ester intermediate => ECO:0000255|HAMAP-Rule:MF_02081, ECO:0000269|PubMed:3148617
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| source |
Swiss-Prot : SWS_FT_FI1
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