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eF-site ID
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6g5k-A |
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PDB Code
|
6g5k |
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Chain
|
A |
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click to enlarge
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Title
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Crystal structure of the binding domain of Botulinum Neurotoxin type B in complex with human synaptotagmin 1 |
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Classification
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TOXIN |
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Compound
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Botulinum neurotoxin type B |
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Source
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(SYT1_HUMAN) |
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Sequence
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A: |
LNNIILNLRYKDNNLIDLSGYGAKVEVYDGVELNDKNQFK
LTSSANSKIRVTQNQNIIFNSVFLDFSVSFWIRIPKYKND
GIQNYIHNEYTIINCMKNNSGWKISIRGNRIIWTLIDING
KTKSVFFEYNIREDISEYINRWFFVTITNNLNNAKIYING
KLESNTDIKDIREVIANGEIIFKLDGDIDRTQFIWMKYFS
IFNTELSQSNIEERYKIQSYSEYLKDFWGNPLMYNKEYYM
FNAGNKNSYIKLKKDSPVGEILTRSKYNQNSKYINYRDLY
IGEKFIIRRKSDDIVRKEDYIYLDFFNLNQEWRVYTYKYF
KKEEEKLFLAPISDSDEFYNTIQIKEYDEQPTYSCQLLFK
KDEESTDEIGLIGIHRFYEEYKDYFCISKWYLKEVKRKPY
NLKLGCNWQFIPKDEGWTELQ
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Description
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Functional site
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1)
|
chain |
A |
| residue |
1189 |
| type |
BINDING |
| sequence |
E
|
| description |
BINDING => ECO:0000269|PubMed:10932256, ECO:0000305|PubMed:14731268, ECO:0007744|PDB:4KBB
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| source |
Swiss-Prot : SWS_FT_FI2
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2)
|
chain |
A |
| residue |
1240 |
| type |
BINDING |
| sequence |
I
|
| description |
BINDING => ECO:0000269|PubMed:10932256, ECO:0000305|PubMed:14731268, ECO:0007744|PDB:4KBB
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
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3)
|
chain |
A |
| residue |
1025 |
| type |
BINDING |
| sequence |
N
|
| description |
BINDING => ECO:0007744|PDB:4KBB
|
| source |
Swiss-Prot : SWS_FT_FI1
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