eF-site ID 6fvg-A PDB Code 6fvg Chain A click to enlarge Title The Structure of CK2alpha with CCh507 bound Classification TRANSFERASE Compound Casein kinase II subunit alpha Source (CSK21_HUMAN) Sequence A:  GPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLV RKLGRGKYSEVFEAINITNNEKVVVKILKPVAAAKIKREI KILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFK QLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNV MIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPEL LVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQL VRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWE RFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHP YFYTVVK Description Functional site 1) chain A residue 36 type sequence Q description binding site for residue E8K A 401 source : AC1 2) chain A residue 39 type sequence Y description binding site for residue E8K A 401 source : AC1 3) chain A residue 41 type sequence L description binding site for residue E8K A 401 source : AC1 4) chain A residue 52 type sequence E description binding site for residue E8K A 401 source : AC1 5) chain A residue 69 type sequence I description binding site for residue E8K A 401 source : AC1 6) chain A residue 70 type sequence L description binding site for residue E8K A 401 source : AC1 7) chain A residue 71 type sequence K description binding site for residue E8K A 401 source : AC1 8) chain A residue 72 type sequence P description binding site for residue E8K A 401 source : AC1 9) chain A residue 103 type sequence D description binding site for residue E8K A 401 source : AC1 10) chain A residue 104 type sequence P description binding site for residue E8K A 401 source : AC1 11) chain A residue 105 type sequence V description binding site for residue E8K A 401 source : AC1 12) chain A residue 106 type sequence S description binding site for residue E8K A 401 source : AC1 13) chain A residue 108 type sequence T description binding site for residue E8K A 401 source : AC1 14) chain A residue 280 type sequence R description binding site for residue E8K A 401 source : AC1 15) chain A residue 45 type sequence L description binding site for residue ATP A 402 source : AC2 16) chain A residue 46 type sequence G description binding site for residue ATP A 402 source : AC2 17) chain A residue 47 type sequence R description binding site for residue ATP A 402 source : AC2 18) chain A residue 53 type sequence V description binding site for residue ATP A 402 source : AC2 19) chain A residue 66 type sequence V description binding site for residue ATP A 402 source : AC2 20) chain A residue 95 type sequence I description binding site for residue ATP A 402 source : AC2 21) chain A residue 114 type sequence E description binding site for residue ATP A 402 source : AC2 22) chain A residue 116 type sequence V description binding site for residue ATP A 402 source : AC2 23) chain A residue 120 type sequence D description binding site for residue ATP A 402 source : AC2 24) chain A residue 158 type sequence K description binding site for residue ATP A 402 source : AC2 25) chain A residue 160 type sequence H description binding site for residue ATP A 402 source : AC2 26) chain A residue 163 type sequence M description binding site for residue ATP A 402 source : AC2 27) chain A residue 174 type sequence I description binding site for residue ATP A 402 source : AC2 28) chain A residue 156 type ACT_SITE sequence D description Proton acceptor source Swiss-Prot : SWS_FT_FI1 29) chain A residue 45-77 type prosite sequence LGRGKYSEVFEAINITNNEKVVVKILKPVAAAK description PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGRGKYSEVFeAinitnnekvvvkilkpv.AAAK source prosite : PS00107 30) chain A residue 152-164 type prosite sequence IMHRDVKPHNVMI description PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. ImHrDVKphNVMI source prosite : PS00108 31) chain A residue 68 type BINDING sequence K description BINDING => ECO:0000255|PROSITE-ProRule:PRU00159 source Swiss-Prot : SWS_FT_FI2 32) chain A residue 45 type BINDING sequence L description BINDING => ECO:0000255|PROSITE-ProRule:PRU00159 source Swiss-Prot : SWS_FT_FI2

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