eF-site ID 6frf-ABCD PDB Code 6frf Chain A, B, C, D click to enlarge Title Crystal structure of CREBBP bromodomain complexd with PA10 Classification TRANSFERASE Compound CREB-binding protein Source (CBP_HUMAN) Sequence A:  MRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQL LGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWL MFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLG B:  IFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIP DYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNN AWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLG C:  IFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIP DYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNN AWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSL D:  IFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIP DYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNN AWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLG Description Functional site 1) chain A residue 1109 type sequence L description binding site for residue E3T A 1201 source : AC1 2) chain A residue 1110 type sequence P description binding site for residue E3T A 1201 source : AC1 3) chain A residue 1113 type sequence Q description binding site for residue E3T A 1201 source : AC1 4) chain A residue 1115 type sequence V description binding site for residue E3T A 1201 source : AC1 5) chain A residue 1120 type sequence L description binding site for residue E3T A 1201 source : AC1 6) chain A residue 1168 type sequence N description binding site for residue E3T A 1201 source : AC1 7) chain A residue 1173 type sequence R description binding site for residue E3T A 1201 source : AC1 8) chain A residue 1174 type sequence V description binding site for residue E3T A 1201 source : AC1 9) chain B residue 1109 type sequence L description binding site for residue E3T B 1201 source : AC2 10) chain B residue 1110 type sequence P description binding site for residue E3T B 1201 source : AC2 11) chain B residue 1113 type sequence Q description binding site for residue E3T B 1201 source : AC2 12) chain B residue 1115 type sequence V description binding site for residue E3T B 1201 source : AC2 13) chain B residue 1120 type sequence L description binding site for residue E3T B 1201 source : AC2 14) chain B residue 1168 type sequence N description binding site for residue E3T B 1201 source : AC2 15) chain B residue 1173 type sequence R description binding site for residue E3T B 1201 source : AC2 16) chain B residue 1174 type sequence V description binding site for residue E3T B 1201 source : AC2 17) chain B residue 1177 type sequence F description binding site for residue E3T B 1201 source : AC2 18) chain C residue 1116 type sequence D description binding site for residue E3T B 1201 source : AC2 19) chain C residue 1119 type sequence L description binding site for residue E3T B 1201 source : AC2 20) chain D residue 1175 type sequence Y description binding site for residue E3T B 1201 source : AC2 21) chain A residue 1175 type sequence Y description binding site for residue E3T C 1201 source : AC3 22) chain B residue 1119 type sequence L description binding site for residue E3T C 1201 source : AC3 23) chain C residue 1109 type sequence L description binding site for residue E3T C 1201 source : AC3 24) chain C residue 1110 type sequence P description binding site for residue E3T C 1201 source : AC3 25) chain C residue 1113 type sequence Q description binding site for residue E3T C 1201 source : AC3 26) chain C residue 1115 type sequence V description binding site for residue E3T C 1201 source : AC3 27) chain C residue 1120 type sequence L description binding site for residue E3T C 1201 source : AC3 28) chain C residue 1168 type sequence N description binding site for residue E3T C 1201 source : AC3 29) chain C residue 1173 type sequence R description binding site for residue E3T C 1201 source : AC3 30) chain C residue 1177 type sequence F description binding site for residue E3T C 1201 source : AC3 31) chain A residue 1120 type sequence L description binding site for residue E3T D 1201 source : AC4 32) chain D residue 1110 type sequence P description binding site for residue E3T D 1201 source : AC4 33) chain D residue 1113 type sequence Q description binding site for residue E3T D 1201 source : AC4 34) chain D residue 1115 type sequence V description binding site for residue E3T D 1201 source : AC4 35) chain D residue 1120 type sequence L description binding site for residue E3T D 1201 source : AC4 36) chain D residue 1168 type sequence N description binding site for residue E3T D 1201 source : AC4 37) chain D residue 1173 type sequence R description binding site for residue E3T D 1201 source : AC4 38) chain D residue 1174 type sequence V description binding site for residue E3T D 1201 source : AC4 39) chain A residue 1108-1167 type prosite sequence SLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQY QEPWQYVDDVWLMFNNAWLY description BROMODOMAIN_1 Bromodomain signature. SlpFrqpvDpqllgipDYFdiVknpMdlstIkrkldtgq..Yqepwqyvddvwl.MfnNAwlY source prosite : PS00633

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