|
eF-site ID
|
6fb6-B |
PDB Code
|
6fb6 |
Chain
|
B |
|
click to enlarge
|
|
Title
|
Crystal Structure of a Tailored I-CreI Homing Endonuclease Protein (3115 variant) in complex with an altered version of its target DNA (Haemoglobin beta subunit gene) at 5NNN region in the presence of Manganese |
Classification
|
DNA BINDING PROTEIN |
Compound
|
I-CreI monomer A |
Source
|
(6FB6) |
|
Sequence
|
B: |
NTKYNKEFLLYLAGFVDGDGSIIAQIKPNQSGKFKHKLSL
TFKVTQKTQRRWFLDKLVDEIGVGYVYDSGSVSNYYLSEI
KPLHNFLTQLQPFLKLKQKQANLVLKIIEQLPSAKESPDK
FLEVCTWVDQVAALNDSKTRKTTSETVRAVLDSL
|
|
Description
|
|
Functional site
|
|
1)
|
chain |
B |
residue |
19 |
type |
|
sequence |
G
|
description |
binding site for residue MN A 201
|
source |
: AC1
|
|
2)
|
chain |
B |
residue |
19 |
type |
|
sequence |
G
|
description |
binding site for residue MN A 202
|
source |
: AC2
|
|
3)
|
chain |
B |
residue |
20 |
type |
|
sequence |
D
|
description |
binding site for residue MN A 202
|
source |
: AC2
|
|
4)
|
chain |
B |
residue |
20 |
type |
|
sequence |
D
|
description |
binding site for residue MN A 203
|
source |
: AC3
|
|
5)
|
chain |
B |
residue |
19 |
type |
catalytic |
sequence |
G
|
description |
233
|
source |
MCSA : MCSA1
|
|
6)
|
chain |
B |
residue |
20 |
type |
catalytic |
sequence |
D
|
description |
233
|
source |
MCSA : MCSA1
|
|
7)
|
chain |
B |
residue |
19 |
type |
BINDING |
sequence |
G
|
description |
|
source |
Swiss-Prot : SWS_FT_FI1
|
|
8)
|
chain |
B |
residue |
20 |
type |
BINDING |
sequence |
D
|
description |
|
source |
Swiss-Prot : SWS_FT_FI1
|
|
|
|