|
eF-site ID
|
6fb2-A |
PDB Code
|
6fb2 |
Chain
|
A |
|
click to enlarge
|
|
Title
|
Crystal Structure of a Tailored I-CreI Homing Endonuclease Protein (3115 variant) in complex with its target DNA (Haemoglobin beta subunit gene) in the presence of Manganese |
Classification
|
DNA BINDING PROTEIN |
Compound
|
DNA endonuclease I-CreI |
Source
|
(6FB2) |
|
Sequence
|
A: |
NTKYNKEFLLYLAGFVDSDGSIIAQIKPNQSVKFKHRLQL
TFDVTQKTQRRWFLDKLVDEIGVGYVADSGSVSKYRLSEI
KPLHNFLTQLQPFLKLKQKQANLVLKIIEQLPSAKESPDK
FLEVCTWVDQIAALNDSKTRKTTSETVRAVLDS
|
|
Description
|
|
Functional site
|
|
1)
|
chain |
A |
residue |
20 |
type |
|
sequence |
D
|
description |
binding site for residue MN A 201
|
source |
: AC1
|
|
2)
|
chain |
A |
residue |
19 |
type |
|
sequence |
S
|
description |
binding site for residue MN A 202
|
source |
: AC2
|
|
3)
|
chain |
A |
residue |
20 |
type |
|
sequence |
D
|
description |
binding site for residue MN A 203
|
source |
: AC3
|
|
|
|