|
eF-site ID
|
6f1t-H |
PDB Code
|
6f1t |
Chain
|
H |
|
click to enlarge
|
|
Title
|
Cryo-EM structure of two dynein tail domains bound to dynactin and BICDR1 |
Classification
|
MOTOR PROTEIN |
Compound
|
ARP1 actin related protein 1 homolog A |
Source
|
ORGANISM_COMMON: Pig; ORGANISM_SCIENTIFIC: Sus scrofa; |
|
Sequence
|
H: |
AALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMV
GMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKI
WHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFE
TFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPI
YEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAE
REIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDG
QVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKC
DVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTM
KIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDES
GPSIVHRKCF
|
|
Description
|
(1) |
ARP1 actin related protein 1 homolog A, Actin, cytoplasmic 1, Actin related protein 10 homolog, Capping protein (Actin filament) muscle Z-line, alpha 1, F-actin capping protein beta subunit, Dynactin Subunit 2, Dynactin Subunit 3, Dynactin 6, Dynactin Subunit 5, BICD family-like cargo adapter 1,BICDR-1, Dynactin Subunit 4, Dynactin Subunit 1, Cytoplasmic dynein 1 heavy chain 1,Dynein Heavy Chain,Cytoplasmic dynein 1 heavy chain 1, Cytoplasmic dynein 1 intermediate chain 2, Cytoplasmic dynein 1 light intermediate chain 2, Dynein light chain roadblock-type 1, BICD family-like cargo adapter 1
|
|
Functional site
|
|
1)
|
chain |
H |
residue |
11 |
type |
|
sequence |
D
|
description |
binding site for residue ATP H 401
|
source |
: AC8
|
|
2)
|
chain |
H |
residue |
13 |
type |
|
sequence |
G
|
description |
binding site for residue ATP H 401
|
source |
: AC8
|
|
3)
|
chain |
H |
residue |
14 |
type |
|
sequence |
S
|
description |
binding site for residue ATP H 401
|
source |
: AC8
|
|
4)
|
chain |
H |
residue |
15 |
type |
|
sequence |
G
|
description |
binding site for residue ATP H 401
|
source |
: AC8
|
|
5)
|
chain |
H |
residue |
16 |
type |
|
sequence |
M
|
description |
binding site for residue ATP H 401
|
source |
: AC8
|
|
6)
|
chain |
H |
residue |
18 |
type |
|
sequence |
K
|
description |
binding site for residue ATP H 401
|
source |
: AC8
|
|
7)
|
chain |
H |
residue |
137 |
type |
|
sequence |
Q
|
description |
binding site for residue ATP H 401
|
source |
: AC8
|
|
8)
|
chain |
H |
residue |
156 |
type |
|
sequence |
G
|
description |
binding site for residue ATP H 401
|
source |
: AC8
|
|
9)
|
chain |
H |
residue |
157 |
type |
|
sequence |
D
|
description |
binding site for residue ATP H 401
|
source |
: AC8
|
|
10)
|
chain |
H |
residue |
210 |
type |
|
sequence |
R
|
description |
binding site for residue ATP H 401
|
source |
: AC8
|
|
11)
|
chain |
H |
residue |
213 |
type |
|
sequence |
K
|
description |
binding site for residue ATP H 401
|
source |
: AC8
|
|
12)
|
chain |
H |
residue |
214 |
type |
|
sequence |
E
|
description |
binding site for residue ATP H 401
|
source |
: AC8
|
|
13)
|
chain |
H |
residue |
302 |
type |
|
sequence |
G
|
description |
binding site for residue ATP H 401
|
source |
: AC8
|
|
14)
|
chain |
H |
residue |
303 |
type |
|
sequence |
T
|
description |
binding site for residue ATP H 401
|
source |
: AC8
|
|
15)
|
chain |
H |
residue |
305 |
type |
|
sequence |
M
|
description |
binding site for residue ATP H 401
|
source |
: AC8
|
|
16)
|
chain |
H |
residue |
306 |
type |
|
sequence |
Y
|
description |
binding site for residue ATP H 401
|
source |
: AC8
|
|
17)
|
chain |
H |
residue |
53-63 |
type |
prosite |
sequence |
YVGDEAQSKRG
|
description |
ACTINS_1 Actins signature 1. YVGDEAQs.KRG
|
source |
prosite : PS00406
|
|
18)
|
chain |
H |
residue |
356-364 |
type |
prosite |
sequence |
WISKQEYDE
|
description |
ACTINS_2 Actins signature 2. WISKqEYDE
|
source |
prosite : PS00432
|
|
19)
|
chain |
H |
residue |
104-116 |
type |
prosite |
sequence |
LLTEAPLNPKANR
|
description |
ACTINS_ACT_LIKE Actins and actin-related proteins signature. LLTEApLNPkaNR
|
source |
prosite : PS01132
|
|
|
|