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eF-site ID
|
6f1t-A |
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PDB Code
|
6f1t |
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Chain
|
A |
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click to enlarge
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Title
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Cryo-EM structure of two dynein tail domains bound to dynactin and BICDR1 |
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Classification
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MOTOR PROTEIN |
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Compound
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ARP1 actin related protein 1 homolog A |
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Source
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ORGANISM_COMMON: Pig; ORGANISM_SCIENTIFIC: Sus scrofa; |
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Sequence
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A: |
IANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHVR
VMAGALEGDIFIGPKAEEHRGLLSIRYPMEHGIVKDWNDM
ERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPRKNRERAAE
VFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTH
AVPIYEGFAMPHSIMRIDIAGRDVSRFLRLYLRKEGYDFH
SSSEFEIVKAIKERACYLSINPQKDETLETEKAQYYLPDG
STIEIGPSRFRAPELLFRPDLIGEESEGIHEVLVFAIQKS
DMDLRRTLFSNIVLSGGSTLFKGFGDRLLSEVKKLAPKDV
KIRISAPQERLYSTWIGGSILASLDTFKKMWVSKKEYEED
GARSIHRKTF
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Description
|
(1) |
ARP1 actin related protein 1 homolog A, Actin, cytoplasmic 1, Actin related protein 10 homolog, Capping protein (Actin filament) muscle Z-line, alpha 1, F-actin capping protein beta subunit, Dynactin Subunit 2, Dynactin Subunit 3, Dynactin 6, Dynactin Subunit 5, BICD family-like cargo adapter 1,BICDR-1, Dynactin Subunit 4, Dynactin Subunit 1, Cytoplasmic dynein 1 heavy chain 1,Dynein Heavy Chain,Cytoplasmic dynein 1 heavy chain 1, Cytoplasmic dynein 1 intermediate chain 2, Cytoplasmic dynein 1 light intermediate chain 2, Dynein light chain roadblock-type 1, BICD family-like cargo adapter 1
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Functional site
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|
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1)
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chain |
A |
| residue |
17 |
| type |
|
| sequence |
G
|
| description |
binding site for residue ADP A 800
|
| source |
: AC1
|
|
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2)
|
chain |
A |
| residue |
18 |
| type |
|
| sequence |
S
|
| description |
binding site for residue ADP A 800
|
| source |
: AC1
|
|
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3)
|
chain |
A |
| residue |
20 |
| type |
|
| sequence |
V
|
| description |
binding site for residue ADP A 800
|
| source |
: AC1
|
|
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4)
|
chain |
A |
| residue |
22 |
| type |
|
| sequence |
K
|
| description |
binding site for residue ADP A 800
|
| source |
: AC1
|
|
|
5)
|
chain |
A |
| residue |
142 |
| type |
|
| sequence |
Q
|
| description |
binding site for residue ADP A 800
|
| source |
: AC1
|
|
|
6)
|
chain |
A |
| residue |
160 |
| type |
|
| sequence |
S
|
| description |
binding site for residue ADP A 800
|
| source |
: AC1
|
|
|
7)
|
chain |
A |
| residue |
161 |
| type |
|
| sequence |
G
|
| description |
binding site for residue ADP A 800
|
| source |
: AC1
|
|
|
8)
|
chain |
A |
| residue |
162 |
| type |
|
| sequence |
D
|
| description |
binding site for residue ADP A 800
|
| source |
: AC1
|
|
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9)
|
chain |
A |
| residue |
218 |
| type |
|
| sequence |
K
|
| description |
binding site for residue ADP A 800
|
| source |
: AC1
|
|
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10)
|
chain |
A |
| residue |
219 |
| type |
|
| sequence |
E
|
| description |
binding site for residue ADP A 800
|
| source |
: AC1
|
|
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11)
|
chain |
A |
| residue |
302 |
| type |
|
| sequence |
G
|
| description |
binding site for residue ADP A 800
|
| source |
: AC1
|
|
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12)
|
chain |
A |
| residue |
303 |
| type |
|
| sequence |
G
|
| description |
binding site for residue ADP A 800
|
| source |
: AC1
|
|
|
13)
|
chain |
A |
| residue |
304 |
| type |
|
| sequence |
S
|
| description |
binding site for residue ADP A 800
|
| source |
: AC1
|
|
|
14)
|
chain |
A |
| residue |
307 |
| type |
|
| sequence |
F
|
| description |
binding site for residue ADP A 800
|
| source |
: AC1
|
|
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15)
|
chain |
A |
| residue |
357-365 |
| type |
prosite |
| sequence |
WVSKKEYEE
|
| description |
ACTINS_2 Actins signature 2. WISKqEYDE
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| source |
prosite : PS00432
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16)
|
chain |
A |
| residue |
109-121 |
| type |
prosite |
| sequence |
LLTEAPLNPRKNR
|
| description |
ACTINS_ACT_LIKE Actins and actin-related proteins signature. LLTEApLNPkaNR
|
| source |
prosite : PS01132
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