|
|
eF-site ID
|
6f09-R |
|
PDB Code
|
6f09 |
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Chain
|
R |
|
click to enlarge
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Title
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Binary complex of 14-3-3 zeta with ubiquitin specific protease 8 (USP8) pSer718 peptide |
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Classification
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SIGNALING PROTEIN |
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Compound
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14-3-3 protein zeta/delta |
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Source
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Homo sapiens (Human) (UBP8_HUMAN) |
|
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Sequence
|
R: |
DKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEER
NLLSVAYKNVVGARRSSWRVVSSIEQKTEGAEKKQQMARE
YREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLKM
KGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQ
PTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIA
LDSEESYKDSTLIMQLLRDNLTLWTS
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Description
|
|
Functional site
|
|
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1)
|
chain |
R |
| residue |
3 |
| type |
MOD_RES |
| sequence |
K
|
| description |
N6-acetyllysine => ECO:0007744|PubMed:19608861
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
2)
|
chain |
R |
| residue |
68 |
| type |
MOD_RES |
| sequence |
K
|
| description |
N6-acetyllysine => ECO:0007744|PubMed:19608861
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
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3)
|
chain |
R |
| residue |
58 |
| type |
MOD_RES |
| sequence |
S
|
| description |
Phosphoserine; by PKA and PKB/AKT1 => ECO:0000269|PubMed:11956222, ECO:0000269|PubMed:12865427, ECO:0000269|PubMed:15883165, ECO:0000269|PubMed:16376338
|
| source |
Swiss-Prot : SWS_FT_FI4
|
|
|
4)
|
chain |
R |
| residue |
184 |
| type |
MOD_RES |
| sequence |
S
|
| description |
Phosphoserine; by MAPK8 => ECO:0000269|PubMed:15071501, ECO:0000269|PubMed:15696159
|
| source |
Swiss-Prot : SWS_FT_FI5
|
|
|
5)
|
chain |
R |
| residue |
207 |
| type |
MOD_RES |
| sequence |
S
|
| description |
Phosphoserine => ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231
|
| source |
Swiss-Prot : SWS_FT_FI6
|
|
|
6)
|
chain |
R |
| residue |
56 |
| type |
MOD_RES |
| sequence |
R
|
| description |
Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
7)
|
chain |
R |
| residue |
127 |
| type |
MOD_RES |
| sequence |
R
|
| description |
Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
8)
|
chain |
R |
| residue |
210 |
| type |
MOD_RES |
| sequence |
S
|
| description |
Phosphoserine => ECO:0000250|UniProtKB:P63102
|
| source |
Swiss-Prot : SWS_FT_FI7
|
|
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