eF-site ID 6f08-I PDB Code 6f08 Chain I click to enlarge Title 14-3-3 zeta in complex with the human Son of sevenless homolog 1 (SOS1) Classification PEPTIDE BINDING PROTEIN Compound 14-3-3 protein zeta/delta Source Homo sapiens (Human) (SOS1_HUMAN) Sequence I:  DKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEER NLLSVAYKNVVGARRSSWRVVSSIEQKEKKQQMAREYREK IETELRDICNDVLSLLEKFLIPNASQAESKVFYLKMKGDY YRYLAEVAAGDKKGIVDQSQQAYQEAFEISKKEMQPTHPI RLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTL SEESYKDSTLIMQLLRDNLTLWTS Description Functional site 1) chain I residue 3 type MOD_RES sequence K description N6-acetyllysine => ECO:0007744|PubMed:19608861 source Swiss-Prot : SWS_FT_FI3 2) chain I residue 68 type MOD_RES sequence K description N6-acetyllysine => ECO:0007744|PubMed:19608861 source Swiss-Prot : SWS_FT_FI3 3) chain I residue 58 type MOD_RES sequence S description Phosphoserine; by PKA and PKB/AKT1 => ECO:0000269|PubMed:11956222, ECO:0000269|PubMed:12865427, ECO:0000269|PubMed:15883165, ECO:0000269|PubMed:16376338 source Swiss-Prot : SWS_FT_FI4 4) chain I residue 184 type MOD_RES sequence S description Phosphoserine; by MAPK8 => ECO:0000269|PubMed:15071501, ECO:0000269|PubMed:15696159 source Swiss-Prot : SWS_FT_FI5 5) chain I residue 207 type MOD_RES sequence S description Phosphoserine => ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231 source Swiss-Prot : SWS_FT_FI6 6) chain I residue 210 type MOD_RES sequence S description Phosphoserine => ECO:0000250|UniProtKB:P63102 source Swiss-Prot : SWS_FT_FI7 7) chain I residue 56 type MOD_RES sequence R description Phosphoserine; by RPS6KA3 => ECO:0000269|PubMed:22827337 source Swiss-Prot : SWS_FT_FI1 8) chain I residue 127 type MOD_RES sequence R description Phosphoserine; by RPS6KA3 => ECO:0000269|PubMed:22827337 source Swiss-Prot : SWS_FT_FI1

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