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eF-site ID
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6epd-M |
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PDB Code
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6epd |
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Chain
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M |
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click to enlarge
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Title
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Substrate processing state 26S proteasome (SPS1) |
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Classification
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HYDROLASE |
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Compound
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Proteasome subunit alpha type-6 |
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Source
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ORGANISM_COMMON: Rat; ORGANISM_SCIENTIFIC: Rattus norvegicus; |
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Sequence
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M: |
EQDGIGEEVLKMSTEEIVQRTRLLDSEIKIMKSEVLRVTH
ELQAMKDKIKENSEKIKVNKTLPYLVSNVIELLDVDPNDQ
EEDGANIDLDSQRKGKCAVIKTSTRQTYFLPVIGLVDAEK
LKPGDLVGVNKDSYLILETLPTEYDSRVKAMEVDERPTEQ
YSDIGGLDKQIQELVEAIVLPMNHKEKFENLGIQPPKGVL
MYGPPGTGKTLLARACAAQTKATFLKLAGPQLVQMFIGDG
AKLVRDAFALAKEKAPSIIFIDELDAIGTKRFDSEKAGDR
EVQRTMLELLNQLDGFQPNTQVKVIAATNRVDILDPALLR
SGRLDRKIEFPMPNEEARARIMQIHSRKMNVSPDVNYEEL
ARCTDDFNGAQCKAVCVEAGMIALRRGATELTHEDYMEGI
LEVQAKKKANLQYYA
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Description
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(1) |
Proteasome subunit alpha type-6 (E.C.3.4.25.1), Proteasome subunit alpha type-2 (E.C.3.4.25.1), Proteasome subunit alpha type-4 (E.C.3.4.25.1), Proteasome subunit alpha type-7 (E.C.3.4.25.1), Proteasome subunit alpha type-5 (E.C.3.4.25.1), Proteasome subunit alpha type-1 (E.C.3.4.25.1), Proteasome subunit alpha type-3 (E.C.3.4.25.1), Proteasome subunit beta type-6 (E.C.3.4.25.1), Proteasome subunit beta type-7 (E.C.3.4.25.1), Proteasome subunit beta type-3 (E.C.3.4.25.1), Proteasome subunit beta type-2 (E.C.3.4.25.1), Proteasome subunit beta type-5 (E.C.3.4.25.1), Proteasome subunit beta type-1 (E.C.3.4.25.1), Proteasome subunit beta type-4 (E.C.3.4.25.1), 26S proteasome subunit S5a, Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14, Proteasome 26S subunit, non-ATPase 8, RCG28037, 26S proteasome non-ATPase regulatory subunit 2, 26S proteasome non-ATPase regulatory subunit 1, Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 3, Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 12, 26S proteasome non-ATPase regulatory subunit 11, Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 6, Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 7 (Predicted), 26S proteasome non-ATPase regulatory subunit 13, 26S proteasome regulatory subunit 7, 26S proteasome regulatory subunit 4, 26S proteasome regulatory subunit 6B, Proteasome 26S subunit, ATPase 6, 26S proteasome regulatory subunit 6A, 26S proteasome regulatory subunit 8
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Functional site
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1)
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chain |
M |
| residue |
379 |
| type |
MOD_RES |
| sequence |
S
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| description |
Phosphoserine => ECO:0000250|UniProtKB:P17980
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| source |
Swiss-Prot : SWS_FT_FI3
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2)
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chain |
M |
| residue |
230 |
| type |
BINDING |
| sequence |
G
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| description |
BINDING => ECO:0000255
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| source |
Swiss-Prot : SWS_FT_FI1
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3)
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chain |
M |
| residue |
329-347 |
| type |
prosite |
| sequence |
VKVIAATNRVDILDPALLR
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| description |
AAA AAA-protein family signature. VkVImATNradtLDpALl.R
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| source |
prosite : PS00674
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