eF-site ID 6epd-J
PDB Code 6epd
Chain J

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Title Substrate processing state 26S proteasome (SPS1)
Classification HYDROLASE
Compound Proteasome subunit alpha type-6
Source ORGANISM_COMMON: Rat; ORGANISM_SCIENTIFIC: Rattus norvegicus;
Sequence J:  MALDGPEQMELEEGKAGSGLRQYYLSKIEELQLIVNDKSQ
NLRRLQAQRNELNAKVRLLREELQLLQEQGSYVGEVVRAM
DKKKVLVKVHPEGKFVVDVDKNIDINDVTPNCRVALRNDS
YTLHKILPNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKE
IKEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLA
RAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMARE
HAPSIIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQL
DGFEATKNIKVIMATNRIDILDSALLRPGRIDRKIEFPPP
NEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVK
GVCTEAGMYALRERRVHVTQEDFEMAVAKVMQKDSEKNMS
IKKLWK
Description (1)  Proteasome subunit alpha type-6 (E.C.3.4.25.1), Proteasome subunit alpha type-2 (E.C.3.4.25.1), Proteasome subunit alpha type-4 (E.C.3.4.25.1), Proteasome subunit alpha type-7 (E.C.3.4.25.1), Proteasome subunit alpha type-5 (E.C.3.4.25.1), Proteasome subunit alpha type-1 (E.C.3.4.25.1), Proteasome subunit alpha type-3 (E.C.3.4.25.1), Proteasome subunit beta type-6 (E.C.3.4.25.1), Proteasome subunit beta type-7 (E.C.3.4.25.1), Proteasome subunit beta type-3 (E.C.3.4.25.1), Proteasome subunit beta type-2 (E.C.3.4.25.1), Proteasome subunit beta type-5 (E.C.3.4.25.1), Proteasome subunit beta type-1 (E.C.3.4.25.1), Proteasome subunit beta type-4 (E.C.3.4.25.1), 26S proteasome subunit S5a, Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14, Proteasome 26S subunit, non-ATPase 8, RCG28037, 26S proteasome non-ATPase regulatory subunit 2, 26S proteasome non-ATPase regulatory subunit 1, Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 3, Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 12, 26S proteasome non-ATPase regulatory subunit 11, Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 6, Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 7 (Predicted), 26S proteasome non-ATPase regulatory subunit 13, 26S proteasome regulatory subunit 7, 26S proteasome regulatory subunit 4, 26S proteasome regulatory subunit 6B, Proteasome 26S subunit, ATPase 6, 26S proteasome regulatory subunit 6A, 26S proteasome regulatory subunit 8


Functional site

1) chain J
residue 222
type MOD_RES
sequence K
description N6-acetyllysine => ECO:0000250|UniProtKB:P62195
source Swiss-Prot : SWS_FT_FI4

2) chain J
residue 289-307
type prosite
sequence IKVIMATNRIDILDSALLR
description AAA AAA-protein family signature. IkVImATNridiLDsALl.R
source prosite : PS00674


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