eF-site ID 6epd-F
PDB Code 6epd
Chain F

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Title Substrate processing state 26S proteasome (SPS1)
Classification HYDROLASE
Compound Proteasome subunit alpha type-6
Source ORGANISM_COMMON: Rat; ORGANISM_SCIENTIFIC: Rattus norvegicus;
Sequence F:  NQYDNDVTVWSPQGRIHQIEYAMEAVKQGSATVGLKSKTH
AVLVALKRAQSELAAHQKKILHVDNHIGISIAGLTADARL
LCNFMRQECLDSRFVFDRPLPVSRLVSLIGSKTQIPTQRY
GRRPYGVGLLIAGYDDMGPHVFQTCPSANYFDCRAMSIGA
RSQSARTYLERHMSEFMQCNLDELVKHGLRALRETLPAEQ
DLTTKNVSIGIVGKDLEFTIYDDDDVSPFLDGLEERPQ
Description (1)  Proteasome subunit alpha type-6 (E.C.3.4.25.1), Proteasome subunit alpha type-2 (E.C.3.4.25.1), Proteasome subunit alpha type-4 (E.C.3.4.25.1), Proteasome subunit alpha type-7 (E.C.3.4.25.1), Proteasome subunit alpha type-5 (E.C.3.4.25.1), Proteasome subunit alpha type-1 (E.C.3.4.25.1), Proteasome subunit alpha type-3 (E.C.3.4.25.1), Proteasome subunit beta type-6 (E.C.3.4.25.1), Proteasome subunit beta type-7 (E.C.3.4.25.1), Proteasome subunit beta type-3 (E.C.3.4.25.1), Proteasome subunit beta type-2 (E.C.3.4.25.1), Proteasome subunit beta type-5 (E.C.3.4.25.1), Proteasome subunit beta type-1 (E.C.3.4.25.1), Proteasome subunit beta type-4 (E.C.3.4.25.1), 26S proteasome subunit S5a, Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14, Proteasome 26S subunit, non-ATPase 8, RCG28037, 26S proteasome non-ATPase regulatory subunit 2, 26S proteasome non-ATPase regulatory subunit 1, Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 3, Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 12, 26S proteasome non-ATPase regulatory subunit 11, Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 6, Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 7 (Predicted), 26S proteasome non-ATPase regulatory subunit 13, 26S proteasome regulatory subunit 7, 26S proteasome regulatory subunit 4, 26S proteasome regulatory subunit 6B, Proteasome 26S subunit, ATPase 6, 26S proteasome regulatory subunit 6A, 26S proteasome regulatory subunit 8


Functional site

1) chain F
residue 208
type MOD_RES
sequence K
description N6-acetyllysine => ECO:0000250|UniProtKB:P43686
source Swiss-Prot : SWS_FT_FI5

2) chain F
residue 6-28
type prosite
sequence YDNDVTVWSPQGRIHQIEYAMEA
description PROTEASOME_ALPHA_1 Proteasome alpha-type subunits signature. YsfslTtFSPsGKlvQIEYAlaA
source prosite : PS00388


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