eF-site ID 6ejg-ABCD PDB Code 6ejg Chain A, B, C, D click to enlarge Title CRYSTAL STRUCTURE OF HUMAN CD81 LARGE EXTRACELLULAR LOOP IN COMPLEX WITH SINGLE CHAIN FV FRAGMENT 4 Classification CELL ADHESION Compound CD81 antigen Source (6EJG) Sequence A:  FVNKDQIAKDVKQFYDQALQQAVVDDDANNAKAVVKTFHE TLDCCGSSTLTALTTSVLKNNLCPSGSNIISNLFKEDCHQ KIDDLFSGK B:  FVNKDQIAKDVKQFYDQALQQAVVDDDANNAKAVVKTFHE TLDCCGSSTLTALTTSVLKNNLCPSGSNIISNLFKEDCHQ KIDDLFSGK C:  DIVLTQSPASLSVSLGQRATISCRASKSVSTSIYSYMHWY QQKPGQPPKLLIKYASYLESGVPARFSGSGSGTDFTLNIH PVEEEDAATYYCEHSREFPFTFGTGTKLEIKQVQLQQSGP ELVKPGASVKISCKASGYTFSSSWMNWVKQRPGKGLEWIG RIYSGDGDAIYNGKFKGKATLTADKSSSTAYMQLSSLTSE DSAVYFCAREGKTGDLLLRSWGQGSALTVSS D:  DIVLTQSPASLSVSLGQRATISCRASKSVSTSIYSYMHWY QQKPGQPPKLLIKYASYLESGVPARFSGSGSGTDFTLNIH PVEEEDAATYYCEHSREFPFTFGTGTKLEIKQVQLQQSGP ELVKPGASVKISCKASGYTFSSSWMNWVKQRPGKGLEWIG RIYSGDGDAIYNGKFKGKATLTADKSSSTAYMQLSSLTSE DSAVYFCAREGKTGDLLLRSWGQGSALTVSS Description (1)  CD81 antigen, SINGLE CHAIN FV FRAGMENT Functional site 1) chain A residue 113-201 type TOPO_DOM sequence FVNKDQIAKDVKQFYDQALQQAVVDDDANNAKAVVKTFHE TLDCCGSSTLTALTTSVLKNNLCPSGSNIISNLFKEDCHQ KIDDLFSGK description Extracellular => ECO:0000269|PubMed:27881302 source Swiss-Prot : SWS_FT_FI1 2) chain B residue 113-201 type TOPO_DOM sequence FVNKDQIAKDVKQFYDQALQQAVVDDDANNAKAVVKTFHE TLDCCGSSTLTALTTSVLKNNLCPSGSNIISNLFKEDCHQ KIDDLFSGK description Extracellular => ECO:0000269|PubMed:27881302 source Swiss-Prot : SWS_FT_FI1 3) chain A residue 116 type SITE sequence K description Important for interaction with integrin => ECO:0000269|PubMed:27993971 source Swiss-Prot : SWS_FT_FI2 4) chain A residue 144 type SITE sequence K description Important for interaction with integrin => ECO:0000269|PubMed:27993971 source Swiss-Prot : SWS_FT_FI2 5) chain A residue 148 type SITE sequence K description Important for interaction with integrin => ECO:0000269|PubMed:27993971 source Swiss-Prot : SWS_FT_FI2 6) chain B residue 116 type SITE sequence K description Important for interaction with integrin => ECO:0000269|PubMed:27993971 source Swiss-Prot : SWS_FT_FI2 7) chain B residue 144 type SITE sequence K description Important for interaction with integrin => ECO:0000269|PubMed:27993971 source Swiss-Prot : SWS_FT_FI2 8) chain B residue 148 type SITE sequence K description Important for interaction with integrin => ECO:0000269|PubMed:27993971 source Swiss-Prot : SWS_FT_FI2

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