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|
eF-site ID
|
6eht-A |
|
PDB Code
|
6eht |
|
Chain
|
A |
|
click to enlarge
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Title
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Modulation of PCNA sliding surface by p15PAF suggests a suppressive mechanism for cisplatin-induced DNA lesion bypass by pol eta holoenzyme |
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Classification
|
DNA BINDING PROTEIN |
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Compound
|
Proliferating cell nuclear antigen |
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Source
|
(6EHT) |
|
|
Sequence
|
A: |
MFEARLVQGSILKKVLEALKDLINEACWDISSSGVNLQSM
DSSHVSLVQLTLRSEGFDTYRCDRNLAMGVNLTSMSKILK
CAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMD
LDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVI
SCAKDGVKFSASGELGNGNIKLSQTSNVDKEEEAVTIEMN
EPVQLTFALRYLNFFTKATPLSSTVTLSMSADVPLVVEYK
IADMGHLKYYLAPK
|
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Description
|
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Functional site
|
|
|
1)
|
chain |
A |
| residue |
61-79 |
| type |
prosite |
| sequence |
RCDRNLAMGVNLTSMSKIL
|
| description |
PCNA_2 Proliferating cell nuclear antigen signature 2. RCDRnlaMgvnLtSMsKIL
|
| source |
prosite : PS00293
|
|
|
2)
|
chain |
A |
| residue |
34-57 |
| type |
prosite |
| sequence |
GVNLQSMDSSHVSLVQLTLRSEGF
|
| description |
PCNA_1 Proliferating cell nuclear antigen signature 1. GVnLqSMDsSHVsLVqLtLrsegF
|
| source |
prosite : PS01251
|
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