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eF-site ID
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6ead-F |
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PDB Code
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6ead |
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Chain
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F |
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click to enlarge
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Title
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CRYSTAL STRUCTURE OF HUMAN RESPIRATORY SYNCYTIAL VIRUS FUSION GLYCOPROTEIN INHIBITOR ESCAPE VARIANT F140I STABILIZED IN THE PREFUSION STATE |
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Classification
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VIRAL PROTEIN |
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Compound
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Fusion glycoprotein F0 |
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Source
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(W8RJF9_HRSV) |
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Sequence
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F: |
NITEEFYQSTCSAVSKGYLSALRTGWYTSVITIELSNIKE
IKCNGTDAKVKLIKQELDKYKNAVTELQLLMQSTPATFLG
ILLGVGSAIASGVAVSKVLHLEGEVNKIKSALLSTNKAVV
SLSNGVSVLTSKVLDLKNYIDKQLLPIVNKQSCSIPNIET
VIEFQQKNNRLLEITREFSVNAGVTTPVSTYMLTNSELLS
LINDMPITNDQKKLMSNNVQIVRQQSYSIMSIIKEEVLAY
VVQLPLYGVIDTPCWKLHTSPLCTTNTKEGSNICLTRTDR
GWYCDNAGSVSFFPQAETCKVQSNRVFCDTMNSLTLPSEV
NLCNVDIFNPKYDCKIMTSKTDVSSSVITSLGAIVSCYGK
TKCTASNKNRGIIKTFSNGCDYVSNKGVDTVSVGNTLYYV
NKQEGKSLYVKGEPIINFYDPLVFPSDEFDASISQVNEKI
NQSLAFIRKS
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Description
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Functional site
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1)
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chain |
F |
| residue |
27 |
| type |
CARBOHYD |
| sequence |
N
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| description |
N-linked (GlcNAc...) asparagine; by host => ECO:0000269|PubMed:21586636
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| source |
Swiss-Prot : SWS_FT_FI3
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2)
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chain |
F |
| residue |
70 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine; by host => ECO:0000269|PubMed:21586636, ECO:0000269|PubMed:28469033
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| source |
Swiss-Prot : SWS_FT_FI4
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3)
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chain |
F |
| residue |
500 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine; by host => ECO:0000269|PubMed:21586636, ECO:0000269|PubMed:24179220
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| source |
Swiss-Prot : SWS_FT_FI6
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