eF-site ID 6e3g-B PDB Code 6e3g Chain B click to enlarge Title Structure of RORgt in complex with a novel agonist. Classification nuclear protein/agonist Compound Nuclear receptor ROR-gamma Source (6E3G) Sequence B:  PYASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSR EEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFM ELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKY GGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTA LVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKTHRQSI LAKLPPKGKLRSLCSQHVERLQIFQHLHPIVVQAAFPPLY KELFS Description Functional site 1) chain B residue 434 type sequence Q description binding site for residue EDO A 601 source : AC1 2) chain B residue 313 type sequence M description binding site for residue EDO B 601 source : AC3 3) chain B residue 391 type sequence L description binding site for residue EDO B 601 source : AC3 4) chain B residue 392 type sequence G description binding site for residue EDO B 601 source : AC3 5) chain B residue 393 type sequence C description binding site for residue EDO B 601 source : AC3 6) chain B residue 482 type sequence R description binding site for residue EDO B 601 source : AC3 7) chain B residue 286 type sequence Q description binding site for residue HOJ B 602 source : AC4 8) chain B residue 317 type sequence W description binding site for residue HOJ B 602 source : AC4 9) chain B residue 320 type sequence C description binding site for residue HOJ B 602 source : AC4 10) chain B residue 323 type sequence H description binding site for residue HOJ B 602 source : AC4 11) chain B residue 324 type sequence L description binding site for residue HOJ B 602 source : AC4 12) chain B residue 361 type sequence V description binding site for residue HOJ B 602 source : AC4 13) chain B residue 377 type sequence F description binding site for residue HOJ B 602 source : AC4 14) chain B residue 378 type sequence F description binding site for residue HOJ B 602 source : AC4 15) chain B residue 379 type sequence E description binding site for residue HOJ B 602 source : AC4 16) chain B residue 388 type sequence F description binding site for residue HOJ B 602 source : AC4 17) chain B residue 391 type sequence L description binding site for residue HOJ B 602 source : AC4 18) chain B residue 400 type sequence I description binding site for residue HOJ B 602 source : AC4 19) chain B residue 479 type sequence H description binding site for residue HOJ B 602 source : AC4

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