eF-site ID 6e3g-ABCD PDB Code 6e3g Chain A, B, C, D click to enlarge Title Structure of RORgt in complex with a novel agonist. Classification nuclear protein/agonist Compound Nuclear receptor ROR-gamma Source (6E3G) Sequence A:  PYASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSR EEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFM ELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKY GGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTA LVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKTHRQSI LAKLPPKGKLRSLCSQHVERLQIFQHLHPIVVQAAFPPLY KELFS B:  PYASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSR EEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFM ELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKY GGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTA LVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKTHRQSI LAKLPPKGKLRSLCSQHVERLQIFQHLHPIVVQAAFPPLY KELFS C:  KILHRLLQ D:  KILHRLLQ Description Functional site 1) chain A residue 313 type sequence M description binding site for residue EDO A 601 source : AC1 2) chain A residue 317 type sequence W description binding site for residue EDO A 601 source : AC1 3) chain A residue 391 type sequence L description binding site for residue EDO A 601 source : AC1 4) chain A residue 392 type sequence G description binding site for residue EDO A 601 source : AC1 5) chain A residue 482 type sequence R description binding site for residue EDO A 601 source : AC1 6) chain B residue 434 type sequence Q description binding site for residue EDO A 601 source : AC1 7) chain A residue 286 type sequence Q description binding site for residue HOJ A 602 source : AC2 8) chain A residue 317 type sequence W description binding site for residue HOJ A 602 source : AC2 9) chain A residue 320 type sequence C description binding site for residue HOJ A 602 source : AC2 10) chain A residue 323 type sequence H description binding site for residue HOJ A 602 source : AC2 11) chain A residue 324 type sequence L description binding site for residue HOJ A 602 source : AC2 12) chain A residue 361 type sequence V description binding site for residue HOJ A 602 source : AC2 13) chain A residue 365 type sequence M description binding site for residue HOJ A 602 source : AC2 14) chain A residue 368 type sequence A description binding site for residue HOJ A 602 source : AC2 15) chain A residue 377 type sequence F description binding site for residue HOJ A 602 source : AC2 16) chain A residue 378 type sequence F description binding site for residue HOJ A 602 source : AC2 17) chain A residue 379 type sequence E description binding site for residue HOJ A 602 source : AC2 18) chain A residue 388 type sequence F description binding site for residue HOJ A 602 source : AC2 19) chain A residue 391 type sequence L description binding site for residue HOJ A 602 source : AC2 20) chain A residue 400 type sequence I description binding site for residue HOJ A 602 source : AC2 21) chain A residue 479 type sequence H description binding site for residue HOJ A 602 source : AC2 22) chain A residue 434 type sequence Q description binding site for residue EDO B 601 source : AC3 23) chain B residue 313 type sequence M description binding site for residue EDO B 601 source : AC3 24) chain B residue 391 type sequence L description binding site for residue EDO B 601 source : AC3 25) chain B residue 392 type sequence G description binding site for residue EDO B 601 source : AC3 26) chain B residue 393 type sequence C description binding site for residue EDO B 601 source : AC3 27) chain B residue 482 type sequence R description binding site for residue EDO B 601 source : AC3 28) chain B residue 286 type sequence Q description binding site for residue HOJ B 602 source : AC4 29) chain B residue 317 type sequence W description binding site for residue HOJ B 602 source : AC4 30) chain B residue 320 type sequence C description binding site for residue HOJ B 602 source : AC4 31) chain B residue 323 type sequence H description binding site for residue HOJ B 602 source : AC4 32) chain B residue 324 type sequence L description binding site for residue HOJ B 602 source : AC4 33) chain B residue 361 type sequence V description binding site for residue HOJ B 602 source : AC4 34) chain B residue 377 type sequence F description binding site for residue HOJ B 602 source : AC4 35) chain B residue 378 type sequence F description binding site for residue HOJ B 602 source : AC4 36) chain B residue 379 type sequence E description binding site for residue HOJ B 602 source : AC4 37) chain B residue 388 type sequence F description binding site for residue HOJ B 602 source : AC4 38) chain B residue 391 type sequence L description binding site for residue HOJ B 602 source : AC4 39) chain B residue 400 type sequence I description binding site for residue HOJ B 602 source : AC4 40) chain B residue 479 type sequence H description binding site for residue HOJ B 602 source : AC4

Display surface Download Links