eF-site ID 6e3e-B PDB Code 6e3e Chain B click to enlarge Title Structure of RORgt in complex with a novel inverse agonist. Classification nuclear protein/agonist Compound Nuclear receptor ROR-gamma Source (RORG_HUMAN) Sequence B:  ASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREE VTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMEL CQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGG MELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALV LINAHRPGLQEKRKVEQLQYNLELAFHHHLCKTHRQSILA KLPPKGKLRSLCSQHVE Description Functional site 1) chain B residue 451 type sequence H description binding site for residue SO4 A 501 source : AC1 2) chain B residue 336 type sequence K description binding site for residue SO4 B 501 source : AC4 3) chain B residue 290 type sequence E description binding site for residue MPD B 502 source : AC5 4) chain B residue 304 type sequence E description binding site for residue MPD B 502 source : AC5 5) chain B residue 311 type sequence K description binding site for residue MPD B 502 source : AC5 6) chain B residue 319 type sequence R description binding site for residue MPD B 502 source : AC5 7) chain B residue 320 type sequence C description binding site for residue HQ7 B 503 source : AC6 8) chain B residue 323 type sequence H description binding site for residue HQ7 B 503 source : AC6 9) chain B residue 324 type sequence L description binding site for residue HQ7 B 503 source : AC6 10) chain B residue 361 type sequence V description binding site for residue HQ7 B 503 source : AC6 11) chain B residue 365 type sequence M description binding site for residue HQ7 B 503 source : AC6 12) chain B residue 368 type sequence A description binding site for residue HQ7 B 503 source : AC6 13) chain B residue 377 type sequence F description binding site for residue HQ7 B 503 source : AC6 14) chain B residue 378 type sequence F description binding site for residue HQ7 B 503 source : AC6 15) chain B residue 379 type sequence E description binding site for residue HQ7 B 503 source : AC6 16) chain B residue 400 type sequence I description binding site for residue HQ7 B 503 source : AC6

Display surface Download Links