eF-site ID 6e1f-ABCD PDB Code 6e1f Chain A, B, C, D click to enlarge Title Crystal structure of the SWIRM domain of human histone lysine-specific demethylase LSD1 Classification OXIDOREDUCTASE Compound Lysine-specific histone demethylase 1A Source (KDM1A_HUMAN) Sequence A:  GPGSLPHDRMTSQEAACFPDIISGPQQTQKVFLFIRNRTL QLWLDNPKIQLTFEATLQQLEAPYNSDTVLVHRVHSYLER HGLINFGIY B:  GPGSLPHDRMTSQEAACFPDIISGPQQTQKVFLFIRNRTL QLWLDNPKIQLTFEATLQQLEAPYNSDTVLVHRVHSYLER HGLINFGIY C:  GPGSLPHDRMTSQEAACFPDIISGPQQTQKVFLFIRNRTL QLWLDNPKIQLTFEATLQQLEAPYNSDTVLVHRVHSYLER HGLINFGIY D:  GPGSLPHDRMTSQEAACFPDIISGPQQTQKVFLFIRNRTL QLWLDNPKIQLTFEATLQQLEAPYNSDTVLVHRVHSYLER HGLINFGIY Description Functional site 1) chain A residue 189 type sequence T description binding site for residue SO4 A 301 source : AC1 2) chain A residue 190 type sequence S description binding site for residue SO4 A 301 source : AC1 3) chain D residue 203 type sequence P description binding site for residue SO4 A 301 source : AC1 4) chain D residue 206 type sequence T description binding site for residue SO4 A 301 source : AC1 5) chain D residue 226 type sequence K description binding site for residue SO4 A 301 source : AC1 6) chain B residue 203 type sequence P description binding site for residue SO4 C 301 source : AC2 7) chain B residue 204 type sequence Q description binding site for residue SO4 C 301 source : AC2 8) chain B residue 226 type sequence K description binding site for residue SO4 C 301 source : AC2 9) chain C residue 189 type sequence T description binding site for residue SO4 C 301 source : AC2 10) chain C residue 190 type sequence S description binding site for residue SO4 C 301 source : AC2 11) chain C residue 191 type sequence Q description binding site for residue SO4 C 301 source : AC2

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