|
|
eF-site ID
|
6dt0-C |
|
PDB Code
|
6dt0 |
|
Chain
|
C |
|
click to enlarge
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Title
|
Cryo-EM structure of a mitochondrial calcium uniporter |
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Classification
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TRANSPORT PROTEIN |
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Compound
|
Mitochondrial calcium uniporter |
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Source
|
(Q7S4I4_NEUCR) |
|
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Sequence
|
C: |
AKGKLLTTPTRLLKLILPLPIQPLALLIHPQQPLSYVERL
IQAELPPVKIPNVYFRAWVRWSSSTEMGDFIRDAARGREF
AIEIEGYNIEMRVSVPSFGDRTYYMRQRLRKMSSEIDGLA
KIKHECDLLAHRSAHRLAKGGFGLLAGWWGVVYYVTFHTE
FGWDLVEPVTYLAGLTTIMGGYLWFLYINRRQHALYEMKG
FDIERWEQLVQDANALRREIRVIAVEYDVDWDETRD
|
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Description
|
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Functional site
|
|
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1)
|
chain |
C |
| residue |
358 |
| type |
|
| sequence |
E
|
| description |
binding site for residue CA A 501
|
| source |
: AC1
|
|
|
2)
|
chain |
C |
| residue |
327-348 |
| type |
TRANSMEM |
| sequence |
RLAKGGFGLLAGWWGVVYYVTF
|
| description |
Helical => ECO:0000269|PubMed:29954988, ECO:0007744|PDB:6DT0
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
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3)
|
chain |
C |
| residue |
356-378 |
| type |
TRANSMEM |
| sequence |
LVEPVTYLAGLTTIMGGYLWFLY
|
| description |
Helical => ECO:0000269|PubMed:29954988, ECO:0007744|PDB:6DT0
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
4)
|
chain |
C |
| residue |
349-355 |
| type |
TOPO_DOM |
| sequence |
HTEFGWD
|
| description |
Mitochondrial intermembrane => ECO:0000305|PubMed:29954988
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
5)
|
chain |
C |
| residue |
358 |
| type |
BINDING |
| sequence |
E
|
| description |
BINDING => ECO:0000269|PubMed:29954988, ECO:0007744|PDB:6DT0
|
| source |
Swiss-Prot : SWS_FT_FI4
|
|
|
|