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eF-site ID
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6drd-C |
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PDB Code
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6drd |
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Chain
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C |
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click to enlarge
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Title
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RNA Pol II(G) |
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Classification
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TRANSFERASE |
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Compound
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DNA-directed RNA polymerase II subunit RPB1 |
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Source
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ORGANISM_COMMON: Human; ORGANISM_SCIENTIFIC: Homo sapiens; |
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Sequence
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C: |
PYANQPTVRITELTDENVKFIIENTDLAVANSIRRVFIAE
VPIIAIDWVQIDANSSVLHDEFIAHRLGLIPLISDDIVDK
LQYSRDCTCEEFCPECSVEFTLDVRCNEDQTRHVTSRDLI
SNSPRVIPVTSRNVEQDDILIVKLRKGQELRLRAYAKKGF
GKEHAKWNPTAGVAFEYDPDNALRHTVYPKPEEWPKSEYS
ELDEDESQAPYDPNGKPERFYYNVESCGSLRPETIVLSAL
SGLKKKLSDLQTQLSHEIQSDV
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Description
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(1) |
DNA-directed RNA polymerase II subunit RPB1 (E.C.2.7.7.6,2.7.7.48), DNA-directed RNA polymerase II subunit RPB2 (E.C.2.7.7.6), DNA-directed RNA polymerase II subunit RPB3, DNA-directed RNA polymerase II subunit RPB4, DNA-directed RNA polymerases I, II, and III subunit RPABC1, DNA-directed RNA polymerases I, II, and III subunit RPABC2, DNA-directed RNA polymerase II subunit RPB7, DNA-directed RNA polymerases I, II, and III subunit RPABC3, DNA-directed RNA polymerase II subunit RPB9, DNA-directed RNA polymerases I, II, and III subunit RPABC5, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerases I, II, and III subunit RPABC4, Gdown1,DNA-directed RNA polymerase II subunit GRINL1A
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Functional site
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1)
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chain |
C |
| residue |
88 |
| type |
|
| sequence |
C
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| description |
binding site for residue ZN C 301
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| source |
: AC1
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2)
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chain |
C |
| residue |
90 |
| type |
|
| sequence |
C
|
| description |
binding site for residue ZN C 301
|
| source |
: AC1
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|
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3)
|
chain |
C |
| residue |
93 |
| type |
|
| sequence |
F
|
| description |
binding site for residue ZN C 301
|
| source |
: AC1
|
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4)
|
chain |
C |
| residue |
94 |
| type |
|
| sequence |
C
|
| description |
binding site for residue ZN C 301
|
| source |
: AC1
|
|
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5)
|
chain |
C |
| residue |
97 |
| type |
|
| sequence |
C
|
| description |
binding site for residue ZN C 301
|
| source |
: AC1
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|
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6)
|
chain |
C |
| residue |
32-72 |
| type |
prosite |
| sequence |
NSIRRVFIAEVPIIAIDWVQIDANSSVLHDEFIAHRLGLI
P
|
| description |
RNA_POL_D_30KD RNA polymerases D / 30 to 40 Kd subunits signature. NSIRRvfiaevpiiAidwVqidaNsSvlhDEfIAhRLGLIP
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| source |
prosite : PS00446
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7)
|
chain |
C |
| residue |
97 |
| type |
ZN_FING |
| sequence |
C
|
| description |
C4-type => ECO:0000269|PubMed:33558764, ECO:0000269|PubMed:33558766, ECO:0000269|PubMed:33674783, ECO:0000312|PDB:7DN3, ECO:0007744|PDB:7AE1, ECO:0007744|PDB:7D58
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| source |
Swiss-Prot : SWS_FT_FI1
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