eF-site ID 6dnz-ABCD PDB Code 6dnz Chain A, B, C, D click to enlarge Title Trypanosoma brucei PRMT1 enzyme-prozyme heterotetrameric complex with AdoHcy Classification GENE REGULATION Compound Arginine N-methyltransferase, putative Source (6DNZ) Sequence A:  DSYSHYGIHXEXLKDCHRTTSYRDAXWRNAYLFKDKVVLD VGCGTGILSXFAAKAGARKVIGVDCSTVAVQAREIVKDNG FEDVITIIQGKVEEIQLDEKVDIIISEWXGYFLLYESXLN TVLCARDNLGTPDVKXFPDKANXHVCGITDEQYIQERFNI WDNVQGIDFSYFKRLSFIEPLVDTVERSQIVTNVAPLVSF DINTVKEADLSFTSEFALEAQASIIYVHALSVHFDTPFTA GHEVVILDTTPYSPPTHWRQTVLYLFNPLRXRAGERATFR XKCSPNALNGRDLDISLHVDFEGALQISHYDQDFRLR B:  RISGNLSCIHDRVRLRAYESVLRSIKGKSVLHLGCGXGLV SXIAARSLASAVVAVDRSAIVDAAQVVANKNGLNNISFFR GALVDVVQNFPVRQFDVIICEWXGPFLINDPLLEEALYAR NNLLASNGVXCPDSSSIHVVGVSDYCFHXDTVEFWGNVYG FKXEPXKALVQREVEXCRVPTSSIVTTTCLAHTVNIASIN NLDDKSSLNDFVVPFSVRATKDTTVNFLTFYIDARFTNPH DPGANFVLGVRPGGTNPWTETSVALHEPLPLKGGEVLSGE LKVCLLNPTRGITTVEVTARTSGNVVNIETKGTYNYQRY C:  DSYSHYGIHXEXLKDCHRTTSYRDAXWRNAYLFKDKVVLD VGCGTGILSXFAAKAGARKVIGVDCSTVAVQAREIVKDNG FEDVITIIQGKVEEIQLDEKVDIIISEWXGYFLLYESXLN TVLCARDNLGTPDVKXFPDKANXHVCGITDEQYIQERFNI WDNVQGIDFSYFKRLSFIEPLVDTVERSQIVTNVAPLVSF DINTVKEADLSFTSEFALEAQASIIYVHALSVHFDTPFTA GHEVVILDTTPYSPPTHWRQTVLYLFNPLRXRAGERATFR XKCSPNALNGRDLDISLHVDFEGALQISHYDQDFRLR D:  RISGNLSCIHDRVRLRAYESVLRSIKGKSVLHLGCGXGLV SXIAARSLASAVVAVDRSAIVDAAQVVANKNGLNNISFFR GALVDVVQNFPVRQFDVIICEWXGPFLINDPLLEEALYAR NNLLASNGVXCPDSSSIHVVGVSDYCFHXDTVEFWGNVYG FKXEPXKALVQREVEXCRVPTSSIVTTTCLAHTVNIASIN NLDDKSSLNDFVVPFSVRATKDTTVNFLTFYIDARFTNPH DPGANFVLGVRPGGTNPWTETSVALHEPLPLKGGEVLSGE LKVCLLNPTRGITTVEVTARTSGNVVNIETKGTYNYQRY Description (1)  Arginine N-methyltransferase, putative Functional site 1) chain A residue 22 type sequence Y description binding site for residue SAH A 401 source : AC1 2) chain A residue 28 type sequence H description binding site for residue SAH A 401 source : AC1 3) chain A residue 37 type sequence R description binding site for residue SAH A 401 source : AC1 4) chain A residue 61 type sequence G description binding site for residue SAH A 401 source : AC1 5) chain A residue 62 type sequence C description binding site for residue SAH A 401 source : AC1 6) chain A residue 66 type sequence I description binding site for residue SAH A 401 source : AC1 7) chain A residue 67 type sequence L description binding site for residue SAH A 401 source : AC1 8) chain A residue 83 type sequence D description binding site for residue SAH A 401 source : AC1 9) chain A residue 84 type sequence C description binding site for residue SAH A 401 source : AC1 10) chain A residue 85 type sequence S description binding site for residue SAH A 401 source : AC1 11) chain A residue 109 type sequence G description binding site for residue SAH A 401 source : AC1 12) chain A residue 110 type sequence K description binding site for residue SAH A 401 source : AC1 13) chain A residue 111 type sequence V description binding site for residue SAH A 401 source : AC1 14) chain A residue 112 type sequence E description binding site for residue SAH A 401 source : AC1 15) chain A residue 126 type sequence E description binding site for residue SAH A 401 source : AC1 16) chain A residue 137 type sequence X description binding site for residue SAH A 401 source : AC1 17) chain A residue 140 type sequence T description binding site for residue SAH A 401 source : AC1 18) chain A residue 169 type sequence D description binding site for residue TRS A 402 source : AC2 19) chain A residue 171 type sequence Q description binding site for residue TRS A 402 source : AC2 20) chain A residue 172 type sequence Y description binding site for residue TRS A 402 source : AC2 21) chain A residue 202 type sequence D description binding site for residue TRS A 402 source : AC2 22) chain A residue 203 type sequence T description binding site for residue TRS A 402 source : AC2 23) chain A residue 208 type sequence Q description binding site for residue TRS A 402 source : AC2 24) chain B residue 102 type sequence H description binding site for residue GOL B 401 source : AC3 25) chain B residue 103 type sequence L description binding site for residue GOL B 401 source : AC3 26) chain B residue 104 type sequence G description binding site for residue GOL B 401 source : AC3 27) chain B residue 171 type sequence E description binding site for residue GOL B 401 source : AC3 28) chain C residue 22 type sequence Y description binding site for residue SAH C 401 source : AC4 29) chain C residue 28 type sequence H description binding site for residue SAH C 401 source : AC4 30) chain C residue 37 type sequence R description binding site for residue SAH C 401 source : AC4 31) chain C residue 61 type sequence G description binding site for residue SAH C 401 source : AC4 32) chain C residue 62 type sequence C description binding site for residue SAH C 401 source : AC4 33) chain C residue 64 type sequence T description binding site for residue SAH C 401 source : AC4 34) chain C residue 66 type sequence I description binding site for residue SAH C 401 source : AC4 35) chain C residue 67 type sequence L description binding site for residue SAH C 401 source : AC4 36) chain C residue 83 type sequence D description binding site for residue SAH C 401 source : AC4 37) chain C residue 84 type sequence C description binding site for residue SAH C 401 source : AC4 38) chain C residue 85 type sequence S description binding site for residue SAH C 401 source : AC4 39) chain C residue 109 type sequence G description binding site for residue SAH C 401 source : AC4 40) chain C residue 110 type sequence K description binding site for residue SAH C 401 source : AC4 41) chain C residue 111 type sequence V description binding site for residue SAH C 401 source : AC4 42) chain C residue 112 type sequence E description binding site for residue SAH C 401 source : AC4 43) chain C residue 137 type sequence X description binding site for residue SAH C 401 source : AC4 44) chain C residue 140 type sequence T description binding site for residue SAH C 401 source : AC4 45) chain C residue 169 type sequence D description binding site for residue TRS C 402 source : AC5 46) chain C residue 172 type sequence Y description binding site for residue TRS C 402 source : AC5 47) chain C residue 202 type sequence D description binding site for residue TRS C 402 source : AC5 48) chain C residue 203 type sequence T description binding site for residue TRS C 402 source : AC5 49) chain C residue 208 type sequence Q description binding site for residue TRS C 402 source : AC5 50) chain D residue 214 type sequence D description binding site for residue GOL D 401 source : AC6 51) chain D residue 217 type sequence F description binding site for residue GOL D 401 source : AC6 52) chain D residue 248 type sequence R description binding site for residue GOL D 401 source : AC6

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