|
eF-site ID
|
6dn0-C |
PDB Code
|
6dn0 |
Chain
|
C |
|
click to enlarge
|
|
Title
|
Retrofitted antibodies with stabilizing mutations: Herceptin scFv mutant with VH K30D and VL S52D. |
Classification
|
IMMUNE SYSTEM |
Compound
|
Human Variable Heavy Chain of Herceptin containing VH mutation K30D |
Source
|
(6DN0) |
|
Sequence
|
C: |
EVQLVESGGGLVQPGGSLRLSCAASGFNIDDTYIHWVRQA
PGKGLEWVARIYPTNGYTRYADSVKGRFTISADTSKNTAY
LQMNSLRAEDTAVYYCSRWGFYAMDVWGQGTLVTVS
|
|
Description
|
|
Functional site
|
|
1)
|
chain |
C |
residue |
19 |
type |
|
sequence |
R
|
description |
binding site for residue FMT A 201
|
source |
: AC1
|
|
2)
|
chain |
C |
residue |
50 |
type |
|
sequence |
R
|
description |
binding site for residue FMT C 201
|
source |
: AC4
|
|
|
|