eF-site ID 6dfn-B PDB Code 6dfn Chain B click to enlarge Title Crystal structure of estrogen receptor alpha in complex with receptor degrader 16aa Classification NUCLEAR PROTEIN Compound Estrogen receptor Source (ESR1_HUMAN) Sequence B:  LALSLTADQMVSALLDAEPPILYSEFSEASMMGLLTNLAD RELVHMINWAKRVPGFVDLTSHDQVHLLECAWLEILMIGL VWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLAT SSRFRMMNLQGEEFVCLKSIILLNSGLEEKDHIHRVLDKI TDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGM EHLYSMKSYDLLLEMLDA Description Functional site 1) chain B residue 497 type sequence L description binding site for residue NI A 602 source : AC2 2) chain B residue 501 type sequence H description binding site for residue NI A 602 source : AC2 3) chain B residue 346 type sequence L description binding site for residue G91 B 601 source : AC3 4) chain B residue 347 type sequence T description binding site for residue G91 B 601 source : AC3 5) chain B residue 349 type sequence L description binding site for residue G91 B 601 source : AC3 6) chain B residue 350 type sequence A description binding site for residue G91 B 601 source : AC3 7) chain B residue 351 type sequence D description binding site for residue G91 B 601 source : AC3 8) chain B residue 353 type sequence E description binding site for residue G91 B 601 source : AC3 9) chain B residue 383 type sequence W description binding site for residue G91 B 601 source : AC3 10) chain B residue 384 type sequence L description binding site for residue G91 B 601 source : AC3 11) chain B residue 388 type sequence M description binding site for residue G91 B 601 source : AC3 12) chain B residue 394 type sequence R description binding site for residue G91 B 601 source : AC3 13) chain B residue 421 type sequence M description binding site for residue G91 B 601 source : AC3 14) chain B residue 424 type sequence I description binding site for residue G91 B 601 source : AC3 15) chain B residue 521 type sequence G description binding site for residue G91 B 601 source : AC3 16) chain B residue 524 type sequence H description binding site for residue G91 B 601 source : AC3 17) chain B residue 525 type sequence L description binding site for residue G91 B 601 source : AC3 18) chain B residue 346 type sequence L description binding site for residue G9J B 602 source : AC4 19) chain B residue 347 type sequence T description binding site for residue G9J B 602 source : AC4 20) chain B residue 350 type sequence A description binding site for residue G9J B 602 source : AC4 21) chain B residue 353 type sequence E description binding site for residue G9J B 602 source : AC4 22) chain B residue 387 type sequence L description binding site for residue G9J B 602 source : AC4 23) chain B residue 394 type sequence R description binding site for residue G9J B 602 source : AC4 24) chain B residue 404 type sequence F description binding site for residue G9J B 602 source : AC4 25) chain B residue 421 type sequence M description binding site for residue G9J B 602 source : AC4 26) chain B residue 424 type sequence I description binding site for residue G9J B 602 source : AC4 27) chain B residue 322 type sequence A description binding site for residue GOL B 603 source : AC5 28) chain B residue 325 type sequence P description binding site for residue GOL B 603 source : AC5 29) chain B residue 356 type sequence H description binding site for residue GOL B 603 source : AC5 30) chain B residue 363 type sequence R description binding site for residue GOL B 603 source : AC5 31) chain B residue 385 type sequence E description binding site for residue GOL B 604 source : AC6 32) chain B residue 452 type sequence I description binding site for residue GOL B 604 source : AC6 33) chain B residue 455 type sequence N description binding site for residue GOL B 604 source : AC6 34) chain B residue 456 type sequence S description binding site for residue GOL B 604 source : AC6 35) chain B residue 511 type sequence L description binding site for residue GOL B 604 source : AC6 36) chain B residue 514 type sequence I description binding site for residue GOL B 604 source : AC6 37) chain B residue 515 type sequence R description binding site for residue GOL B 604 source : AC6 38) chain B residue 537 type MOD_RES sequence Y description Phosphotyrosine; by Tyr-kinases => ECO:0000269|PubMed:7539106 source Swiss-Prot : SWS_FT_FI1 39) chain B residue 447 type LIPID sequence C description S-palmitoyl cysteine => ECO:0000250 source Swiss-Prot : SWS_FT_FI2

Display surface Download Links