eF-site ID 6ddi-C PDB Code 6ddi Chain C click to enlarge Title Crystal Structure of the human BRD2 BD1 bromodomain in complex with a Tetrahydroquinoline analogue Classification Transcription/Inhibitor Compound Bromodomain-containing protein 2 Source (BRD2_HUMAN) Sequence C:  TNQLQYLHKVVMKALWKHQFAWPFRQPVDAVKLGLPDYHK IIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIY NKPTDDIVLMAQTLEKIFLQKVASMPQ Description Functional site 1) chain C residue 132 type sequence N description binding site for residue 03S B 302 source : AC6 2) chain C residue 134 type sequence Y description binding site for residue 03S B 302 source : AC6 3) chain C residue 97 type sequence W description binding site for residue G7V C 301 source : AC8 4) chain C residue 98 type sequence P description binding site for residue G7V C 301 source : AC8 5) chain C residue 101 type sequence Q description binding site for residue G7V C 301 source : AC8 6) chain C residue 110 type sequence L description binding site for residue G7V C 301 source : AC8 7) chain C residue 156 type sequence N description binding site for residue G7V C 301 source : AC8 8) chain C residue 84 type MOD_RES sequence K description Phosphoserine => ECO:0007744|PubMed:19690332 source Swiss-Prot : SWS_FT_FI2 9) chain C residue 159 type BINDING sequence T description BINDING => ECO:0000269|PubMed:37731000, ECO:0007744|PDB:8SB6 source Swiss-Prot : SWS_FT_FI1

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