eF-site ID 6ddi-B PDB Code 6ddi Chain B click to enlarge Title Crystal Structure of the human BRD2 BD1 bromodomain in complex with a Tetrahydroquinoline analogue Classification Transcription/Inhibitor Compound Bromodomain-containing protein 2 Source (BRD2_HUMAN) Sequence B:  TNQLQYLHKVVMKALWKHQFAWPFRQPVDAVKLGLPDYHK IIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIY NKPTDDIVLMAQTLEKIFLQKVASMPQ Description Functional site 1) chain B residue 94 type sequence Q description binding site for residue G7V A 301 source : AC1 2) chain B residue 94 type sequence Q description binding site for residue EDO A 304 source : AC4 3) chain B residue 97 type sequence W description binding site for residue EDO A 304 source : AC4 4) chain B residue 165 type sequence M description binding site for residue EDO A 304 source : AC4 5) chain B residue 97 type sequence W description binding site for residue G7V B 301 source : AC5 6) chain B residue 98 type sequence P description binding site for residue G7V B 301 source : AC5 7) chain B residue 99 type sequence F description binding site for residue G7V B 301 source : AC5 8) chain B residue 110 type sequence L description binding site for residue G7V B 301 source : AC5 9) chain B residue 152 type sequence C description binding site for residue G7V B 301 source : AC5 10) chain B residue 156 type sequence N description binding site for residue G7V B 301 source : AC5 11) chain B residue 97 type sequence W description binding site for residue 03S B 302 source : AC6 12) chain B residue 100 type sequence R description binding site for residue 03S B 302 source : AC6 13) chain B residue 160 type sequence D description binding site for residue EDO B 303 source : AC7 14) chain B residue 161 type sequence D description binding site for residue EDO B 303 source : AC7 15) chain B residue 162 type sequence I description binding site for residue EDO B 303 source : AC7 16) chain B residue 84 type MOD_RES sequence K description Phosphoserine => ECO:0007744|PubMed:19690332 source Swiss-Prot : SWS_FT_FI2 17) chain B residue 159 type BINDING sequence T description BINDING => ECO:0000269|PubMed:37731000, ECO:0007744|PDB:8SB6 source Swiss-Prot : SWS_FT_FI1

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