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eF-site ID
|
6dcw-HLT |
|
PDB Code
|
6dcw |
|
Chain
|
H, L, T |
|
click to enlarge
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Title
|
Crystal structure of human anti-tau antibody CBTAU-27.1 Fab in complex with a human tau peptide |
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Classification
|
IMMUNE SYSTEM |
|
Compound
|
Light chain of CBTAU27.1 Fab |
|
Source
|
(6DCW) |
|
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Sequence
|
H: |
QVQLVESGPEMRKPGESLKISCKTSGYIFSDYWTAWVRQL
PGKGLQWMGIIYSGDSDTRYHPSVQGHVTMSTDSSLTTAY
LQWSSLKASDTGIYYCARLDARVDAGWQLDSWGQGTLVTV
SSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVT
VSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGT
QTYICNVNHKPSNTKVDKRVEPK
|
| L: |
DIQLTQSPDSLAVSLGERATINCKSSQSVFSRDNNKNYLA
WYQHKSGQPPKLLFFWASSRESGVSDRFSGSGSGTDFTLT
IDNLQAEDVALYYCQHYFNTPHNFGQGTKLEIKRTVAAPS
VFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNAL
QSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYAC
EVTHQGLSSPVTKSFNRGE
|
| T: |
YKPVDLSKV
|
|
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Description
|
|
Functional site
|
|
|
1)
|
chain |
L |
| residue |
192-198 |
| type |
prosite |
| sequence |
YACEVTH
|
| description |
IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH
|
| source |
prosite : PS00290
|
|
|
2)
|
chain |
H |
| residue |
206-212 |
| type |
prosite |
| sequence |
YICNVNH
|
| description |
IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH
|
| source |
prosite : PS00290
|
|
|
|