eF-site ID 6dbi-C PDB Code 6dbi Chain C click to enlarge Title Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS nicked DNA intermediates Classification RECOMBINATION/DNA Compound Recombination activating gene 1 - MBP chimera Source (6DBI) Sequence C:  GGRPRQHLLSLTRRAQKHRLRDLKNQVKTFAEKEEGGDVK SVCLTLFLLALRAGNEHKQADELEAMMQGRGFGLHPAVCL AIRVNTFLSCSQYHKMYRTVKATSGRQIFQPLHTLRNAEK ELLPGFHQFEWQPALKNVSTSWDVGIIDGLSGWTVSVDDV PADTISRRFRYDVALVSALKDLEEDIMEGLRERALDDSMC TSGFTVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTIM SISIRLEGEDDGITIFQEQKPNSELSCRPLCLMFVDESDH ETLTAILGPVVAERKAMMESRLIISVGGLLRSFRFFFRGT GYDEKMVREMEGLEASGSTYICTLCDSTRAEASQNMVLHS ITRSHDENLERYEIWRKNPFSESADELRDRVKGVSAKPFM ETQPTLDALHCDIGNATEFYKIFQDEIGEVYQKPNPSREE RRRWRSTLDKQLRKKMKLKPVMRMNGNYARRLMTREAVEA VCELVPSEERREALLKLMDLYLQMKPVWRSTCPSRDCPDQ LCQYSYNSQQFADLLSSMFKYRYDGKITNYLHKTLAHVPE IVERDGSIGAWASEGNESGNKLFRRFRKMNARQSKTFELE DILKHHWLYTSKYLQKFMEAHK Description Functional site 1) chain C residue 749 type sequence C description binding site for residue ZN C 1101 source : AC1 2) chain C residue 752 type sequence C description binding site for residue ZN C 1101 source : AC1 3) chain C residue 959 type sequence H description binding site for residue ZN C 1101 source : AC1 4) chain C residue 964 type sequence H description binding site for residue ZN C 1101 source : AC1 5) chain C residue 684 type sequence E description binding site for residue CA C 1102 source : AC2 6) chain C residue 730 type sequence D description binding site for residue CA C 1102 source : AC2 7) chain C residue 620 type sequence D description binding site for residue CA C 1103 source : AC3 8) chain C residue 621 type sequence G description binding site for residue CA C 1103 source : AC3 9) chain C residue 408-475 type DNA_BIND sequence GGRPRQHLLSLTRRAQKHRLRDLKNQVKTFAEKEEGGDVK SVCLTLFLLALRAGNEHKQADELEAMMQ description NBD => ECO:0000255|PROSITE-ProRule:PRU00820 source Swiss-Prot : SWS_FT_FI3 10) chain C residue 620 type BINDING sequence D description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI4 11) chain C residue 730 type BINDING sequence D description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI4 12) chain C residue 984 type BINDING sequence E description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI4 13) chain C residue 915 type SITE sequence W description Essential for DNA hairpin formation, participates in base-stacking interactions near the cleavage site => ECO:0000250 source Swiss-Prot : SWS_FT_FI6

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