eF-site ID 6db0-A PDB Code 6db0 Chain A click to enlarge Title N-Terminal bromodomain of Human BRD2 with a Tetrahydroquinoline analogue Classification Transcription/Inhibitor Compound Bromodomain-containing protein 2 Source (BRD2_HUMAN) Sequence A:  VTNQLQYLHKVVMKALWKHQFAWPFRQPVDAVKLGLPDYH KIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYI YNKPTDDIVLMAQTLEKIFLQKVASMPQE Description Functional site 1) chain A residue 100 type sequence R description binding site for residue SO4 A 301 source : AC1 2) chain A residue 97 type sequence W description binding site for residue G3J A 302 source : AC2 3) chain A residue 98 type sequence P description binding site for residue G3J A 302 source : AC2 4) chain A residue 99 type sequence F description binding site for residue G3J A 302 source : AC2 5) chain A residue 107 type sequence K description binding site for residue G3J A 302 source : AC2 6) chain A residue 108 type sequence L description binding site for residue G3J A 302 source : AC2 7) chain A residue 110 type sequence L description binding site for residue G3J A 302 source : AC2 8) chain A residue 156 type sequence N description binding site for residue G3J A 302 source : AC2 9) chain A residue 162 type sequence I description binding site for residue G3J A 302 source : AC2 10) chain A residue 94 type sequence Q description binding site for residue G3J B 301 source : AC3 11) chain A residue 84 type MOD_RES sequence K description Phosphoserine => ECO:0007744|PubMed:19690332 source Swiss-Prot : SWS_FT_FI2 12) chain A residue 159 type BINDING sequence T description BINDING => ECO:0000269|PubMed:37731000, ECO:0007744|PDB:8SB6 source Swiss-Prot : SWS_FT_FI1 13) chain A residue 96-155 type prosite sequence AWPFRQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYY WAASECMQDFNTMFTNCYIY description BROMODOMAIN_1 Bromodomain signature. AwpFrqpvDavklglpDYHkiIkqpMdmgtIkrrlenny..Ywaasecmqdfnt.MftNCyiY source prosite : PS00633

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