eF-site ID 6d2p-C PDB Code 6d2p Chain C click to enlarge Title Crystal structure of IOMA-class CLK31 Fab from an HIV-1 naive donor in complex with a germline-targeting gp120 engineered outer domain eOD-GT8 at 2.6 A Classification IMMUNE SYSTEM Compound Germline-targeting HIV-1 gp120 engineered outer domain eOD-GT8 Source (6D2P) Sequence C:  DTITLPCRPAPPPHCSSNITGLILTRQGGYSNANTVIFRP SGGDWRDIARCQIAGTVVSTQLFLNGSLAEEEVVIRSEDW RDNAKSICVQLATSVEIACTGAGHCAISRAKWANTLKQIA SKLREQYGAKTIIFKPSSGGDPEFVNHSFNCGGEFFYCAS TQLFASTWF Description Functional site 1) chain C residue 14 type sequence H description binding site for residue GOL C 201 source : AC1 2) chain C residue 16 type sequence S description binding site for residue GOL C 201 source : AC1 3) chain C residue 17 type sequence S description binding site for residue GOL C 201 source : AC1 4) chain C residue 65 type sequence N description binding site for residue GOL C 201 source : AC1 5) chain C residue 18 type sequence N description binding site for residue GOL C 202 source : AC2 6) chain C residue 96 type sequence E description binding site for residue GOL C 202 source : AC2 7) chain C residue 137 type sequence S description binding site for residue GOL C 203 source : AC3 8) chain C residue 145 type sequence V description binding site for residue GOL C 203 source : AC3 9) chain C residue 146 type sequence N description binding site for residue GOL C 203 source : AC3 10) chain C residue 159 type sequence A description binding site for residue GOL C 203 source : AC3 11) chain C residue 160 type sequence S description binding site for residue GOL C 203 source : AC3 12) chain C residue 161 type sequence T description binding site for residue GOL C 203 source : AC3 13) chain C residue 82 type sequence D description binding site for residue GOL H 302 source : AC5 14) chain C residue 84 type sequence A description binding site for residue GOL H 302 source : AC5 15) chain C residue 85 type sequence K description binding site for residue GOL H 302 source : AC5

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